Uncovering Negative Results: Introducing an Open Access Journal “Journal of Pharmaceutical Negative Results”

Vipra Kundoor; Mueen Ahmed KK

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Uncovering Negative Results: Introducing an Open Access Journal “Journal of Pharmaceutical Negative Results”

机译：发现阴性结果：引入开放获取期刊“药物阴性结果杂志”

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Drug discovery nowadays is a highly innovative process by which new drugs are discovered and/or designed. It is expected that in the year 2010, at least 50% of all new approved drugs will come from the biopharmaceutical sector. The discovery and validation process is mostly carried out by new innovative and medium-sized companies. But, despite advances in technology and greater understanding of biological systems, drug discovery is still a lengthy process. Specialized drug discovery companies need an ideal business climate, that is, political, economic and social conditions, to be able to cope with the entrepreneurial risks of drug development.

机译：如今的药物发现是一种高度创新的过程，通过它可以发现和/或设计新药物。预计到2010年，所有新批准的药物中至少有50％将来自生物制药领域。发现和验证过程主要由新的创新型和中型公司执行。但是，尽管技术进步并且对生物系统有了更多的了解，但是药物发现仍然是一个漫长的过程。专业的药物发现公司需要一种理想的商业环境，即政治，经济和社会条件，以便能够应对药物开发的创业风险。

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《Journal of Young Pharmacists》 |2010年第4期|共3页
作者
Vipra Kundoor; Mueen Ahmed KK;
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中图分类药学;
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1. Uncovering negative results: Introducing an open access journal “Journal of Pharmaceutical Negative Results” [J] . Vipra Kundoor, Mueen K. K. Ahmed Pharmacognosy magazine . 2010,第24期

机译：发现负面结果：引入开放获取期刊“药物负面结果杂志”
2. Uncovering negative results: Introducing an open access journal “Journal of Pharmaceutical Negative Results” [J] . Vipra Kundoor, K. K. Mueen Ahmed Journal of Pharmacology and Pharmacotherapeutics . 2010,第2期

机译：发现负面结果：引入开放获取期刊“药物负面结果杂志”
3. later required open surgery to repair a CSF fistula. For X-Stop, through personal communication, 2 elderly patients with severe comorbidities underwent 1- to 2-level X-Stop lumbar procedures resulting in infection and hematoma, both of which required prolonged hospitalizations. CONCLUSIONS: The literature demonstrates few negative results/complications for minimally invasive spinal surgery. Encouraging more surgeons to submit and more journals to publish negative results for minimally invasive s [J] . Clinical cancer research: an official journal of the American Association for Cancer Research . 2009,第18期

机译：后来需要进行开放性手术以修复CSF瘘管。对于X-Stop，通过个人交流，对2名严重合并症的老年患者进行了1到2级的X-Stop腰椎手术，导致感染和血肿，这两者都需要长期住院。结论：文献显示微创脊柱外科手术几乎没有负面结果/并发症。鼓励更多的外科医生提交更多的期刊，并发表更多的期刊以发表针对微创技术的负面结果
4. Barriers and Negative Nudges: Exploring Challenges in Food Journaling [C] . Felicia Cordeiro, Daniel A. Epstein, Edison Thomaz, Annual CHI Conferenceon Human Factors in Computing Systems . 2015

机译：障碍和消极的讽刺：探索食品日记中的挑战
5. The influence of negative preload and non-synchronous excitations on the performance of tilting pad journal bearings. [D] . Wygant, Karl David. 2001

机译：负预紧力和非同步激励对可倾瓦轴颈轴承性能的影响。
6. Uncovering Negative Results: Introducing an Open Access Journal Journal of Pharmaceutical Negative Results [O] . Vipra Kundoor, Ahmed KK Mueen 2010

机译：发现阴性结果：引入开放获取期刊药物阴性结果杂志
7. Uncovering Negative Results: Introducing an Open Access Journal “Journal of Pharmaceutical Negative Results” [O] . Kundoor, Vipra, Mueen, Ahmed KK 2010

机译：发现阴性结果：引入开放获取期刊“药物阴性结果杂志”

Uncovering Negative Results: Introducing an Open Access Journal “Journal of Pharmaceutical Negative Results”

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