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首页> 外文期刊>Journal of Young Pharmacists >Prescribing Patterns of Antidepressants among Depressive Men in Malaysia: A Survey
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Prescribing Patterns of Antidepressants among Depressive Men in Malaysia: A Survey

机译：马来西亚抑郁症患者抗抑郁药的处方模式：一项调查

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Objective: In recent studies on the prescribing pattern of antidepressants, selective serotonin reuptake inhibitors (SSRIs) were the most prescribed antidepressants in many countries. Yet, little reports investigated depressive populations for antidepressants prescribing in Malaysia. Therefore, this study aimed to explore the pattern of prescribed antidepressants in a Malaysian group of depressive patients throughout their years of depression. Method: A cross-sectional study was conducted on 119 adult male depressive outpatients who were recruited from three psychiatric centers. Patients’ age and duration of depression were recorded, as well as their current and past antidepressants prescribed. Results: Of the study participants, 107 patients (89.9%) were currently antidepressant-treated. Mean age of patients was 49.9 ( SD =11.0), while mean duration of depression was 7.8 years ( SD =6.1). Markedly, SSRIs were the most currently prescribed antidepressants (72.9%), followed by tricyclic antidepressants (TCAs; 10.3%). Moreover, SSRIs predominated the prescribed antidepressants over the years of depression. Additionally, there was an increase in the share of SSRIs prescribing during these years in the expenses of other antidepressants, especially TCAs, whose prescription share fell from 34.1%, in the years preceding 2005, to only 10.3% in the current time. Conclusion: In sum, this study findings concur several reports from various countries, in which SSRI were the most frequent prescribed antidepressants and their prescribing was increasing over nearly the last 10 years. Further research is advocated to explore these findings in larger depression populations.
机译：目的：在有关抗抑郁药处方方式的最新研究中，选择性5-羟色胺再摄取抑制剂（SSRIs）是许多国家中处方最多的抗抑郁药。然而，很少有报道调查抑郁症人群在马来西亚开出的抗抑郁药处方。因此，本研究旨在探讨在马来西亚抑郁症患者的整个抑郁年中处方抗抑郁药的模式。方法：对从三个精神病学中心招募的119名成年男性抑郁症门诊患者进行了横断面研究。记录患者的年龄和抑郁持续时间，以及他们目前和过去的抗抑郁药处方。结果：在研究参与者中，目前有107例患者（占89.9％）接受了抗抑郁药治疗。患者的平均年龄为49.9（SD = 11.0），而平均抑郁持续时间为7.8年（SD = 6.1）。值得注意的是，SSRI是目前最常用的抗抑郁药（72.9％），其次是三环类抗抑郁药（TCA; 10.3％）。此外，在抑郁症的多年中，SSRIs占主导地位的处方抗抑郁药。此外，在这些年中开处方的SSRI在其他抗抑郁药，尤其是三氯乙酸（TCA）的费用中所占的比例有所增加，其处方药份额从2005年之前的34.1％下降到目前的10.3％。结论：总的来说，这项研究结果得到了来自不同国家的几份报告，在这些国家中，SSRI是最常用的处方抗抑郁药，并且在近10年中，他们的处方正在增加。提倡进一步的研究，以探索在较大的抑郁症人群中的这些发现。

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