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首页> 外文期刊>Journal of Young Pharmacists >Inventory management of drugs at a secondary level hospital associated with Ballabgarh HDSS- An experience from North India
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Inventory management of drugs at a secondary level hospital associated with Ballabgarh HDSS- An experience from North India

机译：与Ballabgarh HDSS相关的二级医院的药品库存管理-印度北部的经验

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Objective: Our study includes the investigation of the phytochemical composition and in vitro free radical content and antiinflammatory activity of Mimosa pudica. Materials and Method: Free radical scavenging assay was done to evaluate the dose dependent reduction of free radical by ethanolic extract of Mimosa pudica, this activity was compared with a reference antioxidant i.e. Ascorbic acid. The anti-inflammatory potential of ethanolic extract of Mimosa pudica has been determined by using carrageenan-induced paw edema assay and Cotton wool granuloma in rats. Results: The IC50 of our sample was 24.55 μg/ml, it’s a very much promising result comparing to same reference. At the dose of 300 mg/kg the extract shows considerable inhibitory effect on paw increase 1 hour after carrageenan administration, by inhibiting nearly 50%. The maximum inhibition (43.48%; p Conclusion: This finding suggests that ethanolic extract of M. pudica possess potent anti-inflammatory activity possibly due to its free radical scavenging properties. Key words: Anti-oxidant, Carrageenan, Cotton oil, Inflammation, Mimosa pudica, Paw edema.
机译：目的：我们的研究包括对含羞草的植物化学组成，离体自由基含量和抗炎活性的研究。材料和方法：进行自由基清除试验以评估含羞草乙醇提取物对自由基的剂量依赖性降低，并将该活性与参考抗氧化剂即抗坏血酸进行比较。通过使用角叉菜胶诱导的爪水肿试验和棉绒肉芽肿测定大鼠含羞草乙醇提取物的抗炎潜力。结果：我们样品的IC50为24.55μg/ ml，与相同参考相比，这是非常有希望的结果。在300 mg / kg的剂量下，角叉菜胶给药1小时后，提取物通过抑制近50％表现出明显的抑制爪增长的作用。最大抑制率（43.48％; p结论）：该发现表明，茉莉的乙醇提取物可能具有清除自由基的作用，因此具有强大的抗炎活性。关键词：抗氧化剂，卡拉胶，棉油，炎症，含羞草ud，爪水肿。

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