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Upsurge in BCG Vaccine Induced lymphadenitis: Case Series

机译：卡介苗疫苗诱导的淋巴结炎的热潮：病例系列

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Introduction: Tuberculosis is one of the serious healthcare concerns of the world today. The only vaccine available for tuberculosis till date is the BCG vaccine. It is one of the safest vaccine and is less commonly associated with adverse effects. However, recently we have seen an upsurge in number of BCG vaccine associated lymphadenitis in our hospital. Objective: To report the increase in number of BCG associated lymphadenitis cases in our hospital. Materials and methods: A total of ten cases of BCG associated lymphadenitis were seen in our hospital in the past one year. (May 2016 to April 2017) Data related to vaccination and the course of lymphadenitis was collected from the parents. Observations/Results: Out of the ten cases, 3 were vaccinated outside while the remaining infants were vaccinated in our hospital. Three out of the ten infants required intervention and remaining 7 were reassured and followed up, the swelling subsided in most of them. The most probable cause of the increased incidence in our hospital could be because of a particular batch of vaccine containing an altered strain/ change in the number of viable organism. Conclusion: We are reporting the cases as it might lead to an awareness among other practitioners and will also provide a scope for further studies. Increased surveillance and appropriate treatment guidelines for BCG vaccine associated lymphadenitis is the need of the hour.
机译：简介：结核病是当今世界严重的医疗保健问题之一。迄今为止，唯一可用于结核病的疫苗是BCG疫苗。它是最安全的疫苗之一，很少与不良反应相关。然而，最近我们在医院看到的BCG疫苗相关的淋巴结炎数量激增。目的：报道我院卡介苗相关性淋巴结炎病例增加的情况。资料与方法：一年来我院共发现10例卡介苗相关性淋巴结炎。 （2016年5月至2017年4月）从父母那里收集了与疫苗接种和淋巴结炎的病程有关的数据。观察/结果：在这10例病例中，有3例在室外进行了疫苗接种，而其余婴儿在我院进行了疫苗接种。 10名婴儿中有3名需要干预，其余7名得到了保证和随访，其中大部分肿胀消退。在我们医院中发生率增加的最可能原因可能是由于特定批次的疫苗中含有改变的菌株/活生物体数量的变化。结论：我们正在报告这些病例，因为这可能会引起其他从业者的了解，并且还将提供进一步研究的空间。每小时需要增加BCG疫苗相关淋巴结炎的监测和适当的治疗指南。

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