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Drug Delivery Tailored for the Need– Case Series of Oral Lichen Planus

机译:根据需要量身定制的药物递送–口腔扁平苔藓病例系列

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Lichen planus is an inflammatory mucocutaneous disorder. The pathogenesis of lichen planus is predominantly T cell mediated. The condition is associated with it are hepatitis C, graft versus host disease, medications [antiarrythmic drugs, anti-hypertensive], dental materials [amalgam restoration] etc. Immune modulators have been widely used in the management of lichen planus. Corticosteroids are the most widely used among them. There is various mode of delivering corticosteroids in oral lichen planus. The systemic administration is reported to cause more adverse drug reaction when compared to local drug delivery systems. The case series describes three cases of lichen planus at different sites. It also high lights the site-specific treatment applied in them.
机译:扁平苔藓是一种炎症性粘膜皮肤疾病。扁平苔藓的发病机制主要是T细胞介导的。该病与丙型肝炎,移植物抗宿主病,药物[抗心律失常药物,抗高血压],牙科材料[汞齐修复]等有关。免疫调节剂已广泛用于扁平苔藓的治疗中。皮质类固醇是其中使用最广泛的。在口腔扁平苔藓中有多种递送皮质类固醇的方式。据报道,与局部给药系统相比,全身给药引起更多的药物不良反应。病例系列描述了三个不同部位的扁平苔藓病例。它还高亮显示了在其中应用的针对特定地点的处理方式。

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