...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Journal of Young Pharmacists >Wound healing activity of Chrysophyllum cainito L. leaves: Evaluation in rats using excision wound model
【24h】

Wound healing activity of Chrysophyllum cainito L. leaves: Evaluation in rats using excision wound model

机译：金蝶（Chrysophyllum cainito L.）叶片的伤口愈合活性：使用切除伤口模型评价大鼠

获取原文
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Background: The present study was aimed to evaluate the traditionally reported wound healing potential of Chrysophyllum cainito leaves. Methods: The ethanolic extract of C. cainito leaves was standardized in terms of its gallic acid content (a phenolic compound with wound healing properties) using a validated HPTLC technique. The antioxidant activity of C. cainito leaves was also evaluated in vitro . The wound healing potential of the extract was evaluated in male Albino Wistar rats using excision wound model. The results were statistically evaluated and compared with traditional drug Jatyadi Taila (JT) and modern drug Betadine (BTD). Results: Topical application of the standardized ethanolic extract of C. cainito leaves on excision wounds caused the significantly faster reduction in the wound area as compared to JT and BTD. Similarly, it also showed the significant increase in the tissue biochemical parameters such as hydroxyproline, hexosamine and protein when compared with the untreated control. Conclusion: Findings of the present study provide a baseline data on wound healing and antioxidant potential of C. cainito leaves and supports their traditional claim.
机译：背景：本研究旨在评估传统报道的金藻（Chrysophyllum cainito）叶片的伤口愈合潜力。方法：使用经过验证的HPTLC技术，对C. cainito叶片的乙醇提取物的没食子酸含量（具有伤口愈合特性的酚类化合物）进行标准化。还评估了C. cainito叶片的抗氧化活性。使用切除伤口模型在雄性白化Wistar大鼠中评估提取物的伤口愈合潜力。对结果进行统计学评估，并与传统药物Jatyadi Taila（JT）和现代药物Betadine（BTD）进行比较。结果：与JT和BTD相比，在切除伤口上局部应用标准化的蜡状梭菌乙醇提取物可显着更快地减少伤口面积。同样，与未处理的对照组相比，它也显示出组织生化参数（例如羟脯氨酸，己糖胺和蛋白质）的显着增加。结论：本研究的发现提供了关于念珠菌叶子的伤口愈合和抗氧化潜力的基线数据，并支持其传统主张。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号