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首页> 外文期刊>Journal of Thoracic Disease >Comparison of diagnostic performances among bronchoscopic sampling techniques in the diagnosis of peripheral pulmonary lesions
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Comparison of diagnostic performances among bronchoscopic sampling techniques in the diagnosis of peripheral pulmonary lesions

机译：支气管镜检查技术在周围性肺部病变诊断中的诊断性能比较

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Background: There are many sampling techniques dedicated to radial endobronchial ultrasound (R-EBUS) guided flexible bronchoscopy (FB). However, data regarding the diagnostic performances among bronchoscopic sampling techniques is limited. This study was conducted to compare the diagnostic yields among bronchoscopic sampling techniques in the diagnosis of peripheral pulmonary lesions (PPLs). Methods: A prospective study was conducted on 112 patients who were diagnosed with PPLs and underwent R-EBUS-guided FB between Oct 2012 and Sep 2014. Sampling techniques—including transbronchial biopsy (TBB), brushing cell block, brushing smear, rinsed fluid of brushing, and bronchoalveolar lavage (BAL)—were evaluated for the diagnosis. Results: The mean diameter of the PPLs was 23.5±9.5 mm. The final diagnoses included 76 malignancies and 36 benign lesions. The overall diagnostic yield of R-EBUS-guided bronchoscopy was 80.4%; TBB gave the highest yield among the 112 specimens: 70.5%, 34.8%, 62.5%, 50.0% and 42.0% for TBB, brushing cell block, brushing smear, rinsed brushing fluid, and BAL fluid (BALF), respectively (P Conclusions: TBB provided the highest diagnostic yield; however, to achieve the highest diagnostic performance, TBB, brushing smear and BAL techniques should be performed together.
机译：背景：有许多专门用于放射状支气管内超声（R-EBUS）引导的柔性支气管镜（FB）的采样技术。然而，关于支气管镜取样技术中的诊断性能的数据是有限的。这项研究的目的是比较支气管镜检查技术在诊断周围性肺部病变（PPL）中的诊断率。方法：对2012年10月至2014年9月之间被诊断为PPL并接受R-EBUS引导性FB的112例患者进行了一项前瞻性研究。采样技术包括经支气管活检（TBB），刷洗细胞块，刷涂涂片，冲洗液评估刷牙和支气管肺泡灌洗（BAL）以进行诊断。结果：PPL的平均直径为23.5±9.5 mm。最终诊断包括76例恶性肿瘤和36例良性病变。 R-EBUS引导的支气管镜检查的总诊断率为80.4％;在112个标本中，TBB的产率最高：TBB，刷细胞块，刷涂，冲洗刷液和BAL液（BALF）分别为70.5％，34.8％，62.5％，50.0％和42.0％（P结论： TBB提供了最高的诊断率;但是，要获得最高的诊断性能，应一起执行TBB，刷涂和BAL技术。

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