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首页> 外文期刊>Journal of Thoracic Disease >The impact of low forced vital capacity on behavior restrictions in a population with airflow obstruction
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The impact of low forced vital capacity on behavior restrictions in a population with airflow obstruction

机译：低强制肺活量对气流阻塞人群的行为限制的影响

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Background: Recent studies have suggested that low forced vital capacity (FVC) is related to respiratory symptoms with various comorbid conditions that eventually lead to physical inactivity and may be applied to subjects with airflow obstruction (AO). Therefore, this study aimed to evaluate the association between low FVC and behavior restrictions in subjects with AO. Methods: A cross-sectional study was performed using data from the Korea National Health and Nutrition Survey conducted between 2007 and 2015. Participants aged 40 to 79 years with spirometry-defined AO (pre-bronchodilator forced expiratory volume in one second/FVC Results: A total of 3,345 participants with AO were included. The proportion of subjects with low FVC varied widely according to severity of airflow limitation (0.9%, 35.5%, and 85.1% in the mild, moderate, and severe-to-very-severe AO groups, respectively). Compared to the moderate AO group with normal FVC, those with low FVC were more likely to be older, to be never- or ex-smokers, to have larger waist size with higher body mass index, and to have comorbidities such as diabetes, hypertension, dyslipidemia, and osteoporosis. Low FVC was independently associated with behavior restrictions [adjusted prevalence ratio (aPR), 1.72; 95% confidence interval (CI), 1.43–2.06] among all participants with AO, and this was most prominent in those with moderate AO (aPR, 1.65; 95% CI, 1.27–2.13). Conclusions: In subjects with moderate AO, low FVC was independently associated with behavior restrictions even after adjusting for confounding factors.
机译：背景：最近的研究表明，低的强制肺活量（FVC）与各种合并症的呼吸道症状有关，最终导致缺乏身体活动，并可能适用于气流阻塞（AO）的受试者。因此，本研究旨在评估低FVC与AO受试者行为限制之间的关联。方法：采用2007年至2015年间进行的韩国国家健康与营养调查数据进行横断面研究。年龄在40至79岁之间，肺活量测定定义的AO（支气管扩张剂前强制呼气量在一秒钟/ FVC中）的参与者：总共包括3345名AO参与者，低FVC的受试者比例根据气流受限的严重程度而有很大差异（轻度，中度和重度至重度AO分别为0.9％，35.5％和85.1％与FVC正常的中度AO组相比，FVC低的人群更可能年龄更大，从不吸烟或不吸烟，腰围更大，体重指数更高以及合并症例如，糖尿病，高血压，血脂异常和骨质疏松症。低FVC与行为限制[校正后患病率（aPR）为1.72; 95％置信区间（CI）为1.43-2.06]独立相关，这是最强nt在中度AO患者中（aPR，1.65; 95％CI，1.27-1.23）。结论：在中度AO患者中，即使在调整混杂因素后，低FVC仍独立地与行为限制相关。

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