Improving turnaround time for identifying extended-spectrum β-lactamase-producing Escherichia coli and Klebsiella pneumoniae: experience with the BD Phoenix automated system

Massin Lebitasy; Te-Din Huang; Hector Rodriguez-Villalobos; Anne Simon

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Improving turnaround time for identifying extended-spectrum β-lactamase-producing Escherichia coli and Klebsiella pneumoniae: experience with the BD Phoenix automated system

机译：缩短确定生产广谱β-内酰胺酶的大肠杆菌和肺炎克雷伯菌的周转时间：BD Phoenix自动化系统的经验

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Infections by resistant organisms such asextended-spectrum b -lactamase (ESBL)-producing bacteria represent an increasedrisk of therapeutic failure and areassociated with longer duration of hospitalstay and higher hospital charges. Over thelast decade, Escherichia coli and Klebsiellapneumoniae have been associated withepidemic clones harbouring virulencefactors and multiresistance (Rodr? ′guez-Ban ?o & Pascual, 2008). Thus, it isnecessary to rapidly identify ESBL-producing bacteria to control theirdissemination and to select appropriateantimicrobial therapy (Pitout & Laupland,2008), which is usually non- b -lactams suchas imipenem, fluoroquinolones orcotrimoxazole.

机译：产生耐药谱的细菌，例如产生超广谱β-内酰胺酶（ESBL）的细菌的感染代表了治疗失败的风险增加，并且该地区的住院时间更长，住院费用更高。在过去的十年中，大肠杆菌和肺炎克雷伯氏菌与携带病毒因子和多重耐药性的流行性克隆相关（Rodr？'guez-Ban？o＆Pascual，2008）。因此，有必要迅速鉴定出产生ESBL的细菌以控制其传播并选择适当的抗菌疗法（Pitout＆Laupland，2008），该疗法通常是非β-内酰胺类，如亚胺培南，氟喹诺酮或cotrimoxoxazole。

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《Journal of Medical Microbiology: An Official Journal of the Pathological Society of Great Britain and Ireland》 |2011年第5期|共2页
作者
Massin Lebitasy; Te-Din Huang; Hector Rodriguez-Villalobos; Anne Simon;
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1. Impact of a clonal outbreak of extended-spectrum β-lactamase-producing Klebsiella pneumoniae in the development and evolution of bloodstream infections by K. pneumoniae and Escherichia coli: an 11 year experience in Oxfordshire, UK [J] . D. P. Webster, B. C. Young, R. Morton, Journal of Antimicrobial Chemotherapy . 2011,第9期

机译：产生大范围β-内酰胺酶的肺炎克雷伯菌的克隆暴发对肺炎克雷伯菌和大肠杆菌的血液感染的发展和演变的影响：在英国牛津郡的11年经验
2. Comparison of BDPhoenix and VITEK2 automated antimicrobial susceptibility test systems for extended-spectrum beta-lactamase detection in Escherichia coli and Klebsiella species clinical isolates. [J] . Sturenburg E, Sobottka I, Feucht HH, Diagnostic microbiology and infectious disease . 2003,第1期

机译：BDPhoenix和VITEK2自动化抗菌药敏测试系统在大肠埃希菌和克雷伯菌属临床分离物中的广谱β-内酰胺酶检测的比较。
3. Evaluation of the capability of the VITEK 2 system to detect extended-spectrum β-lactamase-producing Escherichia coli and Klebsiella pneumoniae isolates, in particular with the coproduction of AmpC enzymes [J] . H. M. Chen, J. J. Wu, P. F. Tsai, European Journal of Clinical Microbiology & Infectious Diseases . 2009,第7期

机译：评估VITEK 2系统检测产生广谱β-内酰胺酶的大肠杆菌和肺炎克雷伯菌的能力，尤其是与AmpC酶联产的能力
4. Analysis of Risk Factors for Urinary Tract Infection in Community Inpatients with Extended-spectrum β-lactamase-producing Escherichia Coli [C] . Xiaozhi Yang, Jialin Guo International Conference on Materials Engineering and Information Technology Applications . 2017

机译：扩展β-内酰胺酶大肠杆菌群落住院患者尿路感染危险因素分析
5. Antimicrobial treatment of experimental infection due to an extended-spectrum β-lactamase-producing Klebsiella pneumoniae strain [D] . Mathe, Andras 2007

机译：产生大范围β-内酰胺酶的肺炎克雷伯氏菌菌株对实验性感染的抗菌治疗
6. Evaluation of the Etest ESBL and the BD Phoenix VITEK 1 and VITEK 2 Automated Instruments for Detection of Extended-Spectrum Beta-Lactamases in Multiresistant Escherichia coli and Klebsiella spp. [O] . Maurine A. Leverstein-van Hall, Ad C. Fluit, Armand Paauw, 2002

机译：评估Etest ESBL和BD PhoenixVITEK 1和VITEK 2自动化仪器以检测多重耐药性大肠杆菌和克雷伯氏菌属中的广谱β-内酰胺酶。
7. Improving turnaround time for identifying extended-spectrum β-lactamase-producing Escherichia coli and Klebsiella pneumoniae: experience with the BD Phoenix automated system [O] . Lebitasy Précieux Massin, Huang Te-Din, Rodriguez-Villalobos Hector, 2011

机译：缩短确定生产广谱β-内酰胺酶的大肠杆菌和肺炎克雷伯菌的周转时间：BD Phoenix自动化系统的经验

Improving turnaround time for identifying extended-spectrum β-lactamase-producing Escherichia coli and Klebsiella pneumoniae: experience with the BD Phoenix automated system

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