Validation of Planning Target Volume Margins by Analyzing Intrafractional Localization Errors for 14 Prostate Cancer Patients Based on Three-Dimensional Cross-Correlation between the Prostate Images of Planning CT and Intrafraction Cone-Beam CT during Volumetric Modulated Arc Therapy

KenshiroShiraishi; MasahikoFutaguchi; AkihiroHaga; AkiraSakumi; KatsutakeSasaki; KentaroYamamoto; HiroshiIgaki; KuniOhtomo; KiyoshiYoda; KeiichiNakagawa

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Validation of Planning Target Volume Margins by Analyzing Intrafractional Localization Errors for 14 Prostate Cancer Patients Based on Three-Dimensional Cross-Correlation between the Prostate Images of Planning CT and Intrafraction Cone-Beam CT during Volumetric Modulated Arc Therapy

机译：基于14例前列腺癌患者的分形内定位误差分析计划目标体积裕量的验证，基于计划CT和体积分数锥束CT的前列腺CT图像在体积调制电弧治疗期间的三维互相关

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Time-averaged intreatment prostate localization errors were calculated, for the first time, by three-dimensional prostate image cross-correlation between planning CT and intrafraction kilovoltage cone-beam CT (CBCT) during volumetric modulated arc therapy (VMAT). The intrafraction CBCT volume was reconstructed by an inhouse software after acquiring cine-mode projection images during VMAT delivery. Subsequently, the margin between a clinical target volume and a planning target volume (PTV) was obtained by applying the van Herk and variant formulas using the calculated localization errors. The resulting PTV margins were approximately 2 mm in lateral direction and 4 mm in craniocaudal and anteroposterior directions, which are consistent with the margin prescription employed in our facility.

机译：通过体积调制弧光治疗（VMAT）期间计划CT和分数内千伏锥束CT（CBCT）之间的三维前列腺图像互相关，首次计算了时间平均治疗前列腺的定位误差。在VMAT传送过程中获取电影模式投影图像后，通过内部软件重建了分数内CBCT体积。随后，通过使用计算出的定位误差应用van Herk和变体公式，获得临床目标量与计划目标量（PTV）之间的余量。所产生的PTV边距在横向方向上约为2 mm，在颅尾和前后方向上约为4 mm，这与我们工厂采用的边距处方一致。

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《BioMed research international》 |2014年第1期|共5页
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KenshiroShiraishi; MasahikoFutaguchi; AkihiroHaga; AkiraSakumi; KatsutakeSasaki; KentaroYamamoto; HiroshiIgaki; KuniOhtomo; KiyoshiYoda; KeiichiNakagawa;
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1. Validation of Planning Target Volume Margins by Analyzing Intrafractional Localization Errors for 14 Prostate Cancer Patients Based on Three-Dimensional Cross-Correlation between the Prostate Images of Planning CT and Intrafraction Cone-Beam CT during Volumetric Modulated Arc Therapy [J] . KenshiroShiraishi, MasahikoFutaguchi, AkihiroHaga, BioMed research international . 2014,第2期

机译：基于14例前列腺癌患者的分形内定位误差分析计划目标体积裕量的验证，基于计划CT和体积分数锥束CT的前列腺CT图像在体积调制电弧治疗期间的三维互相关
2. Assessment of three-dimensional setup errors in image-guided pelvic radiotherapy for uterine and cervical cancer using kilovoltage cone-beam computed tomography and its effect on planning target volume margins [J] . Nidhi Patni, Nagarjuna Burela, Rajesh Pasricha, Journal of Cancer Research and Therapeutics . 2017,第1期

机译：用千伏锥束计算机断层扫描评估子宫和宫颈癌的图像引导盆腔放疗中的三维设置误差及其对计划目标体积余量的影响
3. Reduction in patient-reported acute morbidity in prostate cancer patients treated with 81-Gy Intensity-modulated radiotherapy using reduced planning target volume margins and electromagnetic tracking: assessing the impact of margin reduction study. [J] . Sandler HM, Liu PY, Dunn RL, Urology . 2010,第5期

机译：使用减少的计划目标体积余量和电磁跟踪，通过81-Gy强度调制放疗治疗的前列腺癌患者，减少了患者报告的急性发病率：评估降低余量研究的影响。
4. An adversarial machine learning based approach and biomechanically-guided validation for improving deformable image registration accuracy between a planning CT and cone-beam CT for adaptive prostate radiotherapy applications [C] . Anand P Santhanam, Michael Lauria, Brad Stiehl, Conference on Medical Imaging: Image Processing . 2020

机译：一种基于对抗性机器学习的方法和生物力学指导的验证，可提高计划性CT和锥形束CT之间的可变形图像配准精度，以适应性前列腺放射治疗应用
5. Investigation of ultrasound-guided external beam therapy for carcinoma of the prostate: Dosimetric effects of patient repositioning and potential for reduction of PTV margins [D] . Awaj, Eanas 2008

机译：超声引导下束疗法治疗前列腺癌的研究：患者重新定位的剂量学效应和降低PTV幅度的潜力
6. Validation of Planning Target Volume Margins by Analyzing Intrafractional Localization Errors for 14 Prostate Cancer Patients Based on Three-Dimensional Cross-Correlation between the Prostate Images of Planning CT and Intrafraction Cone-Beam CT during Volumetric Modulated Arc Therapy [O] . Kenshiro Shiraishi, Masahiko Futaguchi, Akihiro Haga, -1

机译：基于14例前列腺癌患者在体积调制电弧治疗过程中计划CT的前列腺图像与分数阶锥形束CT的三维互相关分析通过分析分数内定位误差验证计划目标容限
7. Assessment of three-dimensional setup errors in image-guided pelvic radiotherapy for uterine and cervical cancer using kilovoltage cone-beam computed tomography and its effect on planning target volume margins [O] . Nidhi Patni, Nagarjuna Burela, Rajesh Pasricha, 2017

机译：使用千伏锥束计算机断层扫描评估子宫和宫颈癌图像引导盆腔放疗中的三维设置误差及其对规划目标体积边缘的影响

Validation of Planning Target Volume Margins by Analyzing Intrafractional Localization Errors for 14 Prostate Cancer Patients Based on Three-Dimensional Cross-Correlation between the Prostate Images of Planning CT and Intrafraction Cone-Beam CT during Volumetric Modulated Arc Therapy

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