Efficacy and safety of chimeric antigen receptor T-cell (CAR-T) therapy in patients with haematological and solid malignancies: protocol for a systematic review and meta-analysis

Matthew Seftel; Dean A Fergusson; Natasha Kekre; Emma J M Grigor; Kednapa Thavorn; Justin Presseau; Risa Shorr; Harold Atkins; Manoj M Lalu; Mads Daugaard; Robert A Holt; Brian Hutton; Fatima Haggar; Tim Ramsay; Derek Jonker

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Efficacy and safety of chimeric antigen receptor T-cell (CAR-T) therapy in patients with haematological and solid malignancies: protocol for a systematic review and meta-analysis

机译：嵌合抗原受体T细胞（CAR-T）疗法在血液和实体恶性肿瘤中的疗效和安全性：系统评价和荟萃分析的方案

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Abstract Introduction Patients with relapsed or refractory malignancies have a poor prognosis. Immunotherapy with chimeric antigen receptor T (CAR-T) cells redirects a patient?￠??s immune cells against the tumour antigen. CAR-T cell therapy has demonstrate

机译：摘要简介复发性或难治性恶性肿瘤患者预后较差。嵌合抗原受体T（CAR-T）细胞的免疫疗法使患者的免疫细胞针对肿瘤抗原重新定向。 CAR-T细胞疗法已证明

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《BMJ Open》 |2017年第12期|共页
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Matthew Seftel; Dean A Fergusson; Natasha Kekre; Emma J M Grigor; Kednapa Thavorn; Justin Presseau; Risa Shorr; Harold Atkins; Manoj M Lalu; Mads Daugaard; Robert A Holt; Brian Hutton; Fatima Haggar; Tim Ramsay; Derek Jonker;
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中图分类临床医学;
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1. Efficacy and safety of chimeric antigen receptor T-cell (CAR-T) therapy in patients with haematological and solid malignancies: protocol for a systematic review and meta-analysis [J] . Matthew Seftel, Dean A Fergusson, Natasha Kekre, BMJ Open . 2017,第12期

机译：嵌合抗原受体T细胞（CAR-T）疗法在血液和实体恶性肿瘤中的疗效和安全性：系统评价和荟萃分析的方案
2. Adoptive Immunotherapy for B-cell Malignancies Using CD19-Targeted Chimeric Antigen Receptor T-Cells: A Systematic Review of Efficacy and Safety [J] . Hao Lu, Li Tongtong, Chang Lung-Ji, Current medicinal chemistry . 2019,第17期

机译：使用CD19靶向嵌合抗原受体T细胞的B细胞恶性肿瘤的采用免疫疗法：对疗效和安全性的系统审查
3. Risks and Benefits of Chimeric Antigen Receptor T-Cell (CAR-T) Therapy in Cancer: A Systematic Review and Meta-Analysis [J] . Grigor Emma J. M., Fergusson Dean, Kekre Natasha, Transfusion medicine reviews . 2019,第2期

机译：嵌合抗原受体T细胞（CAR-T）治疗癌症的风险和益处：系统评价和荟萃分析
4. Main Issues and Current Strategies in Enhancing the Efficacy of Chimeric Antigen Receptor T-Cell Therapy among Tumor Treatments [C] . Zhengting He International Conference on Frontiers of Biological Sciences and Engineering . 2020

机译：提高嵌合抗原受体T细胞治疗肿瘤治疗疗效的主要问题及目前策略
5. The Curative Potential of Chimeric Antigen Receptor T-Cell Therapy for B-Cell Malignancies. [D] . Koduri, Megha Pallavi. 2017

机译：嵌合抗原受体T细胞疗法对B细胞恶性肿瘤的治疗潜力。
6. Efficacy and safety of chimeric antigen receptor T-cell (CAR-T) therapy in patients with haematological and solid malignancies: protocol for a systematic review and meta-analysis [O] . Emma J M Grigor, Dean A Fergusson, Fatima Haggar, 2017

机译：嵌合抗原受体T细胞（CAR-T）治疗血液和实体恶性肿瘤的疗效和安全性：系统评价和荟萃分析的方案
7. Chimeric Antigen Receptor T-cell (CAR T) Therapy for Hematologic and Solid Malignancies: Efficacy and Safety—A Systematic Review with Meta-Analysis [O] . Wen-Liang Yu, Zi-Chun Hua 2019

机译：嵌合抗原受体T细胞（CAR T）血液学和固体恶性肿瘤治疗：疗效和安全性 - 通过META分析进行系统审查

Efficacy and safety of chimeric antigen receptor T-cell (CAR-T) therapy in patients with haematological and solid malignancies: protocol for a systematic review and meta-analysis

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