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首页> 外文期刊>BMJ Open >Study protocol for a randomised controlled trial comparing the efficiency of two provider-endorsed manual paediatric fluid resuscitation techniques
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Study protocol for a randomised controlled trial comparing the efficiency of two provider-endorsed manual paediatric fluid resuscitation techniques

机译：一项随机对照试验的研究方案，比较了两种提供者认可的手动儿科液体复苏技术的效率

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Introduction Paediatric shock is a life-threatening condition with many possible causes and a global impact. Current resuscitation guidelines require rapid fluid administration as a cornerstone of paediatric shock management. However, little evidence is available to inform clinicians how to most effectively perform rapid fluid administration where this is clinically required, resulting in suboptimal knowledge translation of current resuscitation guidelines into clinical practice. Objectives This study aims to determine which of the two commonly used techniques for paediatric fluid resuscitation (disconnect–reconnect technique and push–pull technique) yields a higher fluid administration rate in a simulated clinical scenario. Secondary objectives include determination of catheter dislodgement rates, subjective and objective measures of provider fatiguability and descriptive information regarding any technical issues encountered with performance of each method under the study. Methods and analysis This study will utilise a randomised crossover trial design. Participants will include consenting healthcare providers from McMaster Children's Hospital. Each participant will administer 900?ml (60?ml/kg) of normal saline to a simulated 15?kg infant as quickly as possible on two separate occasions using the manual fluid administration techniques under the study. The primary outcome, rate of fluid administration, will be evaluated using a paired two-tailed Student t test. Ethics and dissemination This protocol has been approved by the Hamilton Health Sciences Research Ethics Board. Results These will be published in a peer-reviewed scientific journal and presented at one or more scientific conferences. Protocol Registration Protocol Registered on ClinicalTrials.gov NCT01774214
机译：简介小儿电击是一种危及生命的疾病，可能有许多可能的原因，并具有全球影响。当前的复苏指南要求快速输液作为小儿休克管理的基石。然而，几乎没有证据可告知临床医生如何在临床上需要的情况下最有效地执行快速输液，导致当前复苏指南转化为临床实践的知识不足。目的本研究旨在确定在模拟临床情况下两种常用的儿科液体复苏技术（断连-再连接技术和推挽式技术）中哪个能产生更高的输液速率。次要目标包括确定导管移位率，提供者疲劳的主观和客观测量以及与研究中每种方法的执行所遇到的任何技术问题有关的描述性信息。方法和分析本研究将利用随机交叉试验设计。参加者将包括McMaster儿童医院的同意的医疗保健提供者。使用本研究中的手动输液技术，每位参与者将在两次单独的情况下，尽快在模拟的15？kg婴儿中给予900？ml（60？ml / kg）生理盐水。主要结局（输液速度）将通过配对的两尾学生t检验进行评估。道德与传播该协议已获得汉密尔顿健康科学研究伦理委员会的批准。结果这些将发表在同行评审的科学杂志上，并在一个或多个科学会议上发表。协议注册协议已在ClinicalTrials.gov上注册NCT01774214

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