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首页> 外文期刊>British Journal of Cancer >Plasma protein profiles and prognosis in gastric cancer
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Plasma protein profiles and prognosis in gastric cancer

机译：胃癌患者血浆蛋白谱与预后

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In 104 patients with gastric cancer the serum proteins carcinoembryonic antigen (CEA), C-reactive protein (CRP), alpha 1-acid glycoprotein (AGP) (orosomucoid) and alpha 1-antichymotrypsin (ACT) were measured pre-operatively. The estimated median survival of patients with both raised CEA and ACT was only 5 weeks in contrast to 64 weeks for those with both proteins normal. An intermediary group with one of these proteins raised and the other normal had an estimated median survival of 15 weeks. Similar results were obtained by considering a combination of CEA with either AGP or CRP. For these data the results were not explicable in terms of associations between survival time and patient's age, stage, operative procedure, histological classification or site of primary tumour.
机译：在104例胃癌患者中，术前测定了血清蛋白癌胚抗原（CEA），C反应蛋白（CRP），α1酸性糖蛋白（AGP）（类类骨粉）和α1抗胰凝乳蛋白酶（ACT）。 CEA和ACT均升高的患者的估计中位生存期仅为5周，而两种蛋白均正常的患者的中位生存期仅为64周。中间群体中，其中一种蛋白质升高，另一种正常，估计中位生存期为15周。通过考虑将CEA与AGP或CRP结合使用可获得类似的结果。对于这些数据，就生存时间与患者的年龄，阶段，手术程序，组织学分类或原发肿瘤部位之间的关联而言，结果尚无法解释。

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