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首页> 外文期刊>British Journal of Cancer >Sunburn, suntan and the risk of cutaneous malignant melanoma – The Western Canada Melanoma Study
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Sunburn, suntan and the risk of cutaneous malignant melanoma – The Western Canada Melanoma Study

机译:晒伤,晒黑和皮肤恶性黑色素瘤的风险–加拿大西部黑色素瘤研究

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A comparison of interview data on 595 patients with newly incident cutaneous melanoma, excluding lentigo maligna melanoma and acral lentiginous melanoma, with data from comparison subjects drawn from the general population, showed that melanoma risk increased in association with the frequency and severity of past episodes of sunburn, and also that melanoma risk was higher in subjects who usually had a relatively mild degree of suntan compared to those with moderate or deep suntan in both winter and summer. The associations with sunburn and with suntan were independent. Melanoma risk is also increased in association with a tendency to burn easily and tan poorly and with pigmentation characteristics of light hair and skin colour, and history freckles; the associations with sunburn and suntan are no longer significant when these other factors are taken into account. This shows that pigmentation characteristics, and the usual skin reaction to sun, are more closely associated with melanoma risk than are sunburn and suntan histories.
机译:将595名新近发生的皮肤黑色素瘤患者(不包括lentigo恶性黑色素瘤和acral慢性黑色素瘤)的访谈数据与来自一般人群的比较对象进行比较,结果表明,黑色素瘤的风险与过去发作的频率和严重程度有关与通常在冬季和夏季都有中度或深度晒黑的受试者相比,通常晒黑程度相对较轻的受试者的晒黑风险更高。与晒伤和晒黑的关联是独立的。黑色素瘤的风险也随着容易燃烧和棕褐色变差以及浅色的头发和皮肤的色素沉着特征以及历史性雀斑而增加;当考虑到其他因素时,与晒伤和晒黑的关联就不再重要。这表明,与晒黑和晒黑史相比,色素沉着特征和通常的皮肤对太阳的反应与黑色素瘤风险更紧密相关。

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