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首页> 外文期刊>British Journal of Cancer >Staging quality is related to the survival of women with endometrial cancer: a Scottish population based study.Deficient surgical staging and omission of adjuvant radiotherapy is associated with poorer survival of women diagnosed with endometrial cancer in Scotland during 1996 and 1997
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Staging quality is related to the survival of women with endometrial cancer: a Scottish population based study.Deficient surgical staging and omission of adjuvant radiotherapy is associated with poorer survival of women diagnosed with endometrial cancer in Scotland during 1996 and 1997

机译:分期质量与子宫内膜癌妇女的生存有关:一项基于苏格兰人群的研究。外科分期不足和辅助放疗的遗漏与1996年至1997年期间苏格兰诊断为子宫内膜癌的妇女的较差生存有关。

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The association between treatment variation and survival of women with endometrial cancer was investigated. A retrospective cohort based upon the complete Scottish population registered on in-patient and day-case hospital discharge data (Scottish Morbidity Record-1) and cancer registration (Scottish Morbidity Record-6) coded C54 and C55 in ICD10, between 1st January 1996 to 31st December 1997 were analysed. Seven hundred and three patients who underwent surgical treatment out of 781 patients that were diagnosed with endometrial cancer in Scotland during 1996 and 1997. The overall quality of surgical staging was poor. The quality of staging was related to both the year that the surgeon passed the Member of the Royal College of Obstetricians and Gynaecologists examination and also to ‘specialist’ status but was not related to surgeon caseload. Two clinically important prognostic factors were found to be associated with survival; whether the International Federation of Obstetrics and Gynaecology stage was documented, RHR=2.0 (95% CI=1.3 to 3.1) and also to the use of adjuvant radiotherapy, RHR=2.2 (95% CI=1.5 to 3.5). The associations with survival were strongest in patients with advanced disease, International Federation of Obstetrics and Gynaecology stages 1C through to stage 3. Deficiencies in staging and variations in the use of adjuvant radiotherapy represent a possible source of avoidable mortality in patients with endometrial cancer. Consequently, there should be a greater emphasis on improving the overall quality of surgical staging in endometrial cancer.
机译:研究了子宫内膜癌妇女的治疗差异与生存之间的关系。根据1996年1月1日至2006年之间在ICD10中以C54和C55编码的C54和C55,根据在住院和日间医院出院数据(苏格兰病历记录1)和癌症注册(苏格兰病历记录6)上注册的全部苏格兰人口进行的回顾性队列研究。分析了1997年12月31日。在1996年至1997年期间,在苏格兰被诊断患有子宫内膜癌的781例患者中,有733例接受了手术治疗。手术分期的总体质量较差。分期的质量不仅与外科医生通过皇家妇产科医师学院检查的年份有关,而且与“专家”身份有关,但与外科医生的病案数量无关。发现两个临床上重要的预后因素与生存有关。是否记录了国际妇产科联合会的阶段,RHR = 2.0(95%CI = 1.3至3.1)以及使用辅助放疗,RHR = 2.2(95%CI = 1.5至3.5)。在晚期疾病的患者中,与生存的关联最强,国际妇产科联合会从1C到第3阶段。分期的不足和辅助放疗的使用差异是子宫内膜癌患者可避免的死亡的可能来源。因此,应该更加重视改善子宫内膜癌手术分期的整体质量。

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