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首页> 外文期刊>British Journal of Cancer >Hepatitis-B surface antigen and antibody in Bantu patients with primary hepatocellular cancer
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Hepatitis-B surface antigen and antibody in Bantu patients with primary hepatocellular cancer

机译:班图族原发性肝细胞癌患者的乙型肝炎表面抗原和抗体

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Hepatitis-B surface antigen (HBsAg) was found in the serum of 58 of 158 (36-4%) southern African Bantu patients with primary hepatocellular cancer by counter immunoelectrophoresis and in 94 (59-5%) by radioimmunoassay (RIA). The prevalence of this antigen in the general Bantu population using these methods was 7% and 9% respectively. Antibody against HBsAg was detected in 11-6% of the patients by passive haemagglutination (PH) and 13-4% by RIA, and in 33-4% (by PH) of a control population. Antibody sub-types were predominantly "adw" (69-2%) with a lesser frequency of "ayw" (23%), while 7-8% were indeterminate. The corresponding figures in the controls were 80-4, 8-4 and 11-2%. HBsAg was more common in younger patients. No relationship could be demonstrated between hepatitis-B antigenaemia and the presence of alpha-foetoprotein in high concentration, although there were far fewer patients in the alpha-foetoprotein-negative group.
机译:通过反向免疫电泳在158例南部非洲班图族原发性肝细胞癌患者中的58例(36-4%)血清中发现了乙型肝炎表面抗原(HBsAg),通过放射免疫法(RIA)在94例(59-5%)中发现了乙型肝炎表面抗原(HBsAg)。使用这些方法,该抗原在普通班图人人群中的流行率分别为7%和9%。被动血凝(PH)患者中有11-6%的患者检测到HBsAg抗体,RIA检出了13-4%的患者,而对照人群中检出的患者的33-4%(通​​过PH)。抗体亚型主要是“ adw”(69-2%),而“ ayw”(23%)的频率较低,而7-8%的不确定。对照中的相应数字为80-4、8-4和11-2%。乙肝表面抗原在年轻患者中更为常见。乙型肝炎抗原血症和高浓度的甲胎蛋白之间没有关系,尽管甲胎蛋白阴性组的患者少得多。

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