In vivo RAF signal transduction as a potential biomarker for sorafenib efficacy in patients with neuroendocrine tumours

M Quintela-Fandino; M Krzyzanowska; G Duncan; A Young; M J Moore; E X Chen; A Stathis; R Colomer; J Petronis; M Grewal; S Webster; L Wang; L L Siu

首页> 外文期刊>British Journal of Cancer >In vivo RAF signal transduction as a potential biomarker for sorafenib efficacy in patients with neuroendocrine tumours

【24h】

In vivo RAF signal transduction as a potential biomarker for sorafenib efficacy in patients with neuroendocrine tumours

机译：体内RAF信号转导是索拉非尼在神经内分泌肿瘤患者中疗效的潜在生物标志物

获取原文

掌桥外文数据库（机构版） >>

开具论文收录证明 >>

文献代查 >>

页面导航

摘要
著录项
相似文献
相关主题

摘要

Background:Targeted therapies elicit anticancer activity by exerting pharmacodynamic effects on specific molecular targets. Currently, there is limited use of pharmacodynamic assessment to guide drug administration in the routine oncology setting.

机译：背景：靶向疗法通过在特定分子靶标上发挥药效学作用来引发抗癌活性。目前，在常规肿瘤学背景下，药效学评估在指导药物管理方面的应用有限。

著录项

来源
《British Journal of Cancer》 |2013年第6期|共8页
作者
M Quintela-Fandino; M Krzyzanowska; G Duncan; A Young; M J Moore; E X Chen; A Stathis; R Colomer; J Petronis; M Grewal; S Webster; L Wang; L L Siu;
展开▼
作者单位

展开▼
收录信息
原文格式 PDF
正文语种
中图分类肿瘤学;
关键词

相似文献

外文文献
中文文献
专利

1. Biomarker analysis beyond angiogenesis: RAS/RAF mutation status, tumour sidedness, and second-line ramucirumab efficacy in patients with metastatic colorectal carcinoma from RAISE-a global phase III study [J] . Yoshino T., Portnoy D. C., Obermannova R., Annals of oncology: official journal of the European Society for Medical Oncology . 2019,第1期

机译：血管生成的生物标志物分析：RAS / RAF突变状态，肿瘤相位性和二线Ramucirumab患者从提高全球第三阶段研究中的转移性结肠直肠癌
2. The Raf Kinase Inhibitor Sorafenib Inhibits JAK-STAT Signal Transduction in Human Immune Cells [J] . del Campo Sara E. Martin, Levine Kala M., Mundy-Bosse Bethany L., The Journal of Immunology: Official Journal of the American Association of Immunologists . 2015,第5期

机译：Raf激酶抑制剂索拉非尼抑制人免疫细胞中的JAK-STAT信号转导。
3. The Raf Kinase Inhibitor Sorafenib Inhibits JAK–STAT Signal Transduction in Human Immune Cells [J] . Sara E. Martin del Campo, Kala M. Levine, Bethany L. Mundy-Bosse, The journal of immunology . 2015,第5期

机译：Raf激酶抑制剂索拉非尼抑制人免疫细胞中的JAK–STAT信号转导。
4. A Mathematical Modeling of Signal Transduction Cascade on Raf-Akt Cross-Talk [C] . Mariko Hatakeyama, Shuhei Kimura, Noriko Yumoto, Workshop on Genome Informatics . 2002

机译：RAF-AKT串扰信号转导级联的数学建模
5. Investigations of the biodistribution and phototherapeutic utility of two palladium(II)-containing macrocyclic drugs in a tumour-bearing mouse model: A study of the pharmacokinetics and tissue distribution of the potential photodynamic drug palladium-bacteriopheophorbide as well as the in vivo treatment efficacy and tissue distribution of the potential photothermal drug palladium(II) octabutoxynaphthalocyanine. [D] . DeGroot, Jennifer Leanne. 2002

机译：两种含钯（II）的大环药物在荷瘤小鼠模型中的生物分布和光疗实用性的研究：潜在的光动力药物钯-细菌脱镁叶绿酸的药代动力学和组织分布以及体内治疗效果和研究光热药物钯（II）八丁氧基萘酞菁的组织分布。
6. In vivo RAF signal transduction as a potential biomarker for sorafenib efficacy in patients with neuroendocrine tumours [O] . M Quintela-Fandino, M Krzyzanowska, G Duncan, 2013

机译：体内RAF信号转导是索拉非尼在神经内分泌肿瘤患者中疗效的潜在生物标志物
7. In vivo RAF signal transduction as a potential biomarker for sorafenib efficacy in patients with neuroendocrine tumours [O] . M Quintela-Fandino, M Krzyzanowska, G Duncan, 2013

机译：在体内RAF信号转导作为神经内分泌肿瘤患者的索拉非尼疗效的潜在生物标志物

In vivo RAF signal transduction as a potential biomarker for sorafenib efficacy in patients with neuroendocrine tumours

摘要

著录项

相似文献

相关主题

期刊订阅