A predictive role for noncancerous prostate cells: low connexin-26 expression in radical prostatectomy tissues predicts metastasis

I V Bijnsdorp; L Rozendaal; R J A van Moorselaar; A A Geldof

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A predictive role for noncancerous prostate cells: low connexin-26 expression in radical prostatectomy tissues predicts metastasis

机译：非癌性前列腺细胞的预测作用：前列腺癌根治术组织中低连接蛋白-26的表达预测转移

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Background:It is important to identify markers that predict whether prostate cancer will metastasise. The adjacent noncancerous cells (influenced by the tumour cells) may also express potential markers. The objective of this study was to determine the influence of cancer cells on noncancerous cells and to assess the value of the cell-communication protein connexin-26 (Cx26) as a marker to predict the development of metastasis.

机译：背景：识别预测前列腺癌是否会转移的标志很重要。相邻的非癌细胞（受肿瘤细胞影响）也可能表达潜在的标志物。这项研究的目的是确定癌细胞对非癌细胞的影响，并评估细胞通讯蛋白连接蛋白26（Cx26）作为预测转移发生的标志物的价值。

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《British Journal of Cancer》 |2012年第12期|共6页
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I V Bijnsdorp; L Rozendaal; R J A van Moorselaar; A A Geldof;
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中图分类肿瘤学;
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1. Time to Disease Recurrence Is a Predictor of Metastasis and Mortality in Patients with High-risk Prostate Cancer Who Achieved Undetectable Prostate-specific Antigen Following Robot-assisted Radical Prostatectomy [J] . Kim Do Kyung, Koo Kyo Chul, Lee Kwang Suk, Journal of Korean medical science. . 2018,第45期

机译：疾病复发的时间是高危前列腺癌患者的转移和死亡率的预测因素，这些患者在机器人辅助的根治性前列腺切除术后获得了无法检测的前列腺特异性抗原
2. Emphasizing the role of Wnt5a protein expression to predict favorable outcome after radical prostatectomy in patients with low‐grade prostate cancer [J] . Azharuddin Sajid Syed Khaja, Lars Egevad, Leszek Helczynski, Cancer Medicine . 2012,第1期

机译：强调Wnt5a蛋白表达在低度前列腺癌患者根治性前列腺切除术后预测良好结局中的作用
3. Gleason pattern 5 is the strongest pathologic predictor of recurrence, metastasis, and prostate cancer-specific death in patients receiving salvage radiation therapy following radical prostatectomy [J] . JacksonW., HamstraD.A., JohnsonS., Cancer: A Journal of the American Cancer Society . 2013,第18期

机译：格里森模式5是根治性前列腺切除术后接受抢救放疗的患者复发，转移和前列腺癌特异性死亡的最强病理预测指标
4. Pretreatment Serum Testosterone Level Can Predict Pathological Stage in Localized Prostate Cancer Patients Treated with Radical Prostatectomy [C] . T. Imamoto, H. Suzuki, S. Fukasawa, International Congress of Andrology . 2005

机译：预处理血清睾酮水平可以预测局部前列腺癌患者的病理阶段，其患有自由基前列腺切除术治疗
5. An integrated companion diagnostics assay for predicting biochemical recurrence following radical prostatectomy. [D] . Lee, George C. 2014

机译：用于预测前列腺癌根治术后生化复发的综合伴随诊断测定。
6. A predictive role for noncancerous prostate cells: low connexin-26 expression in radical prostatectomy tissues predicts metastasis [O] . I V Bijnsdorp, L Rozendaal, R J A van Moorselaar, 2012

机译：非癌性前列腺细胞的预测作用：前列腺癌根治术组织中低连接蛋白-26表达可预测转移
7. A predictive role for noncancerous prostate cells: low connexin-26 expression in radical prostatectomy tissues predicts metastasis [O] . I V Bijnsdorp, L Rozendaal, R J A van Moorselaar, 2012

机译：非癌前列腺细胞的预测作用：在自由基前列腺切除术组织中低connecxin-26表达预测转移

A predictive role for noncancerous prostate cells: low connexin-26 expression in radical prostatectomy tissues predicts metastasis

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