首页> 外文期刊>British Journal of Cancer >Prenatal X-ray exposure and childhood brain tumours: a population-based case|[ndash]|control study on tumour subtypes
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Prenatal X-ray exposure and childhood brain tumours: a population-based case|[ndash]|control study on tumour subtypes

机译:产前X射线暴露与儿童脑瘤:基于人群的肿瘤亚型病例对照研究

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We investigated childhood brain tumours by histological subtype in relation to prenatal X-ray among all children, less than 15 years of age, born in Sweden between 1975 and 1984. For each case, one control was randomly selected from the Medical Birth Register, and exposure data on prenatal X-ray were extracted blindly from antenatal medical records. Additional information on maternal reproductive history was obtained from the Medical Birth Register. We found no overall increased risk for childhood brain tumour after prenatal abdominal X-ray exposure (adjusted odds ratio (OR): 1.02, 95% confidence interval (CI): 0.64–1.62); primitive neuroectodermal tumours had the highest risk estimate (OR: 1.88, 95% CI: 0.92–3.83).
机译:我们在1975年至1984年之间出生于瑞典的所有15岁以下儿童中,按照与产前X射线相关的组织学亚型,对儿童期脑肿瘤进行了调查。对于每种情况,均从“医疗出生登记册”中随机选择一个对照,从产前医疗记录中盲目提取出产前X射线的暴露数据。有关孕产妇生殖史的其他信息,可从《医疗出生登记册》中获得。我们发现,产前腹部X线暴露后儿童期脑肿瘤的总体风险没有增加(调整后的优势比(OR):1.02,95%置信区间(CI):0.64–1.62);原始神经外胚层肿瘤的风险估计最高(OR:1.88,95%CI:0.92-3.83)。

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