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首页> 外文期刊>Clinical Chemistry: Journal of the American Association for Clinical Chemists >Clinical value of immunoradiometric assay of thyrotropin for patients with nonthyroidal illness and taking various drugs.
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Clinical value of immunoradiometric assay of thyrotropin for patients with nonthyroidal illness and taking various drugs.

机译:甲状腺素的免疫放射测定对非甲状腺疾病和服用各种药物的临床价值。

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Using a two-site immunoradiometric assay, we measured concentrations of thyrotropin (TSH) in serum of 134 clinically euthyroid subjects, 93 patients with nonthyroidal illness, and 80 patients who were being treated with various drugs. Abnormal concentrations of TSH, free thyroxin, and free triiodothyronine, respectively, were recorded in serum of three (3.2%), 19 (20.4%), and 37 (39.8%) of the patients with nonthyroidal illness and in three (3.8%), five (6.3%), and 10 (12.5%) of the patients taking drugs. TSH could be detected in all patients' serum samples. We conclude that, for most patients without thyroid disease, a basal (i.e., unstimulated) measurement of their TSH concentration in serum will indicate their thyroid status more reliably than will assay of free thyroxin or free triiodothyronine.
机译:使用两点免疫放射分析法,我们测量了134名临床甲状腺功能正常受试者,93例非甲状腺疾病患者和80例接受各种药物治疗的患者血清中促甲状腺激素(TSH)的浓度。非甲状腺疾病患者的三名(3.2%),19名(20.4%)和37名(39.8%)的血清中以及三名(3.8%)的血清中分别记录了TSH,游离甲状腺素和游离三碘甲状腺氨酸的异常浓度。 ,五(6.3%)和10(12.5%)的患者正在服药。在所有患者的血清样本中都可以检测到TSH。我们得出的结论是,对于大多数无甲状腺疾病的患者,对血清中TSH浓度的基础(即未刺激)测量将比对游离甲状腺素或游离三碘甲甲状腺素的测定更可靠地表明其甲状腺状态。

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