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Pro/con clinical debate: Are steroids useful in the management of patients with septic shock?

机译:赞成/反对派临床辩论:类固醇激素对脓毒性休克患者的治疗有用吗?

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Decision-making in the intensive care unit is often very difficult. Although we are encouraged to make evidence-based decisions, this may be difficult for a number of reasons. To begin with, evidence may not exist to answer the clinical question. Second, when there is evidence it may not be applicable to the patient in question or the clinician may be reluctant to apply it to the patient based on a number of secondary issues such as costs, premorbid condition or possible complications. Finally, emotions are often highly charged when caring for patients that have a significant chance of death, and care-givers as well as families are frequently prepared to take chances on a therapy whose benefit is not entirely clear. Steroid use in septic shock is an example of a therapy that makes some sense but has conflicting support in the literature. In this issue of Critical Care Forum, the two sides of this often heated debate are brought to the forefront in an interesting format.Keywords: glucocorticoids, sepsis, shock
机译:重症监护室的决策通常非常困难。尽管我们被鼓励做出基于证据的决定,但是由于多种原因,这可能很难。首先,可能不存在回答临床问题的证据。其次,当有证据表明它可能不适用于所讨论的患者时,或者临床医生可能会基于许多次要问题(例如费用,病态或可能的并发症)不愿将其应用于患者。最后,在照料有重大死亡机会的患者时,情绪往往带有很高的负担,并且护理人员和家人经常准备好利用机会进行治疗,其益处尚不完全清楚。在败血性休克中使用类固醇是一种有一定意义但在文献中有相互矛盾的支持的治疗方法。在本期《重症监护论坛》(Critical Care Forum)中,这个经常引起激烈争论的话题以有趣的形式被带到了最前沿。关键词:糖皮质激素,败血症,休克

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