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首页> 外文期刊>Critical care : >Prediction of fluid challenge effect: filling pressure when left ventricular function is abnormal, diastolic volume when left ventricular function is normal
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Prediction of fluid challenge effect: filling pressure when left ventricular function is abnormal, diastolic volume when left ventricular function is normal

机译：体液挑战效果的预测：左心功能异常时的充盈压，左心功能正常时的舒张压

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Fluid resuscitation is a cornerstone of intensive care unit patient care, but prediction of the cardiovascular response remains difficult, despite many efforts in clinical research. The concept of responders and nonresponders illustrates such a difficulty. Many techniques have been tested, from strictly non-invasive to invasive, delivering various parameters related to the fluid challenge response. Considering the physical parameters available, such as pressure, volume and flow generated by right and left pumps circulating in elastic or compliant tubes, it sounds useful to go back to the basic knowledge to discuss the results of the present article. This published study tested in the postoperative period of cardiovascular surgery the prediction obtained with filling pressures and the diastolic volume. When left ventricular function (global ejection fraction) is adequate, the volume before fluid administration seems to predict well the fluid challenge response; whereas when the global ejection fraction is poor, the filling pressure seems more suitable. The present commentary discusses the main physiological issues related to these findings, with some methodological aspects.
机译：液体复苏是重症监护病房患者护理的基石，但尽管在临床研究中进行了许多努力，但仍难以预测心血管反应。响应者和不响应者的概念说明了这种困难。从严格的非侵入性到侵入性，已经测试了许多技术，这些技术可提供与体液激发反应相关的各种参数。考虑到可用的物理参数，例如在弹性管或顺应管中循环的左右泵产生的压力，体积和流量，回到基础知识讨论本文的结果听起来很有用。这项发表的研究测试了心血管外科手术后的充盈压和舒张压的预测值。当左心室功能（总体射血分数）足够时，输液前的体积似乎可以很好地预测输液反应。反之，当整体喷射率差时，填充压力似乎更合适。本评论讨论一些方法方面与这些发现有关的主要生理问题。

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