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Current practice in the management of tetanus

机译：破伤风管理的现行做法

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Tetanus is still a scourge among the under-privileged populations of the world, and unfortunately remains an important cause of death although a cheap, safe and highly efficacious vaccine is available. The rarity of the disease in some parts of the world results in newly trained physicians being unable to make a clinical diagnosis, and hampers the conduct of adequately powered randomized controlled trials. Several new and experimental pharmacological agents are being used to control the spasms in tetanus, and to combat the autonomic instability that occurs in the disease. New evidence is emerging regarding the use of antibiotics and intrathecal immunoglobulin in tetanus. It is imperative, therefore, that all physicians working in critical care should be aware of the current advances and evidence-based guidelines for management of tetanus in order to achieve the best outcomes, which Rodrigo and colleagues have reviewed in a recent issue of Critical Care.
机译：破伤风仍然是世界贫困人口中的祸害，尽管可以买到便宜，安全和高效的疫苗，但破伤风仍然是重要的死亡原因。在世界某些地区，这种疾病的稀有性导致新近训练的医生无法做出临床诊断，并且妨碍了进行足够有力的随机对照试验的开展。几种新的和实验性的药理学药物被用于控制破伤风中的痉挛，并抵抗疾病中发生的自主神经不稳定。关于破伤风中使用抗生素和鞘内免疫球蛋白的新证据正在出现。因此，至关重要的是，所有从事重症监护的医生都应了解破伤风的最新进展和循证指南，以达到最佳效果，Rodrigo及其同事在最近一期的《重症监护》中对其进行了审查。 。

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