...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Applied and Environmental Microbiology >Differential Inhibition of Mollicute Growth: an Approach to Development of Selective Media for Specific Mollicutes
【24h】

Differential Inhibition of Mollicute Growth: an Approach to Development of Selective Media for Specific Mollicutes

机译：分子生长的差异抑制：一种针对特定Mollicuts选择性培养基的开发方法。

获取原文
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

The energy-generating pathways of Mycoplasma spp. are diverse. Thus, it was predicted that the ability of inhibitors of these pathways to block growth would vary among species. This prediction was tested with 14 Mycoplasma species and potential inhibitors. The greatest differentiation among test species was obtained using fluoride, iodoacetate (IAA), β-fluoropyruvate (FP), cibacron blue (CB), l-citrulline, and carbonyl cyanide m-chlorophenylhydrazone. A range of other potential inhibitors, including l-arginine analogues, had little inhibitory effect on growth, and d-arginine was shown to be a growth substrate for arginine-hydrolyzing species. Fluoride selectively inhibited the growth of mycoplasmas that were able only to ferment sugars to lactate and/or to hydrolyze arginine. In contrast, IAA was most effective against organic acid-oxidizing species, and l-citrulline inhibited arginine-hydrolyzing species. Mycoplasma verecundum, a species for which energy sources have not been identified, was relatively resistant to FP. Similarly, Acholeplasma laidlawii was distinguished by its CB resistance.
机译：支原体的能量产生途径。是多种多样的。因此，据预测，这些途径的抑制剂阻止生长的能力在物种之间会有所不同。使用14种支原体物种和潜在抑制剂测试了这一预测。使用氟化物，碘乙酸盐（IAA），β-氟丙酮酸盐（FP），香巴兰蓝（CB），L-瓜氨酸和羰基氰化物间氯苯hydr获得最大的区分。一系列其他潜在的抑制剂，包括l-精氨酸类似物，对生长几乎没有抑制作用，而d-精氨酸被证明是精氨酸水解物种的生长底物。氟化物选择性抑制支原体的生长，这种支原体只能使糖发酵为乳酸和/或水解精氨酸。相反，IAA对有机酸氧化物种最有效，而L-瓜氨酸抑制精氨酸水解物种。 Verecundum verecundum是一种尚未发现能源的物种，对FP具有相对抗性。同样地，无窝霍乱血浆以其CB抗性而著称。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号