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Effect of Streptomycin on Some Enzyme Systems of Bacillus subtilis

机译:链霉素对枯草芽孢杆菌某些酶系统的影响

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Streptomycin slightly inhibited lactic and malic dehydrogenases of Bacillus subtilis, and inhibited isocitric dehydrogenase to about 60%. The formation of lactic dehydrogenase, glutamic dehydrogenase, α-alanine dehydrogenase, and succinic dehydrogenase was stimulated by the antibiotic at a concentration causing 50% inhibition of bacterial growth. Streptomycin had practically no influence on the formation of malic dehydrogenase, but the antibiotic produced 48% inhibition of the synthesis of isocitric dehydrogenase.
机译:链霉素对枯草芽孢杆菌的乳酸和苹果酸脱氢酶有轻微的抑制作用,而对同基因的脱氢酶则抑制约60%。乳酸脱氢酶,谷氨酸脱氢酶,α-丙氨酸脱氢酶和琥珀酸脱氢酶的形成受到抗生素的刺激,其浓度可抑制细菌生长50%。链霉素对苹果酸脱氢酶的形成几乎没有影响,但抗生素对同型脱氢酶的合成产生了48%的抑制作用。

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