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Isolation and Characterization of an Isolate (HN) of Marek's Disease Virus with Low Pathogenicity

机译:低致病性马立克氏病病毒的分离株(HN)的分离和鉴定

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A cytopathic agent was isolated and characterized as an isolate of Marek's disease herpesvirus (MDHV) with low pathogenicity, and referred to as the HN isolate. This isolate of MDHV did not cause clinical Marek's disease (MD) or death in a highly susceptible line of chickens within 5 weeks after exposure. Gross lesions of limited extent were noted in a few of the inoculated birds. Microscopic nerve lesions in the inoculated and contact-infected birds were invariably minimal, closely resembling C-type MD lesions.
机译:分离出一种细胞致病剂,并将其表征为具有低致病性的马立克氏病疱疹病毒(MDHV)的分离株,称为HN分离株。分离出的MDHV不会在暴露后5周内在高度易感的鸡系中引起临床马立克氏病(MD)或死亡。在几只已接种的禽只中,肉眼可见的病变程度有限。接种和接触感染的鸟类的微观神经损伤总是很小,非常类似于C型MD损伤。

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