Newcastle disease virus in allantoamnionic fluid was photosensitized with acridine orange, and then photodynamically inactivated. The inactivation rate was directly proportional to light intensity and to dye concentrations up to a level of approximately 100 to 200 μg/ml. Inactivation occurred at approximately an exponential rate for the first 4.5 log10 units of virus, and then continued at a decreasing rate.
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