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Bacteriophage Types and Antibiotic Susceptibility of Staphylococcus aureus

机译:金黄色葡萄球菌的噬菌体类型和抗生素敏感性

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In vitro tests of 132 strains of Staphylococcus aureus, among which were 38 (28.7%) heteroresistant strains, were performed with 14 commonly used antibiotics, including gentamicin and vancomycin. Heteroresistant strains were found predominantly, but not only, with group 3 phage-typable strains; no heteroresistant strain was found in out-patients. Gentamicin appeared as a uniformly effective agent at low concentrations against oxacillin-sensitive and -resistant strains. It is suggested that gentamicin should be compared to vancomycin in future clinical therapeutic trials in severe staphylococcal infections, especially in cases due to oxacillin-resistant strains.
机译:用14种常用抗生素(包括庆大霉素和万古霉素)对132株金黄色葡萄球菌进行了体外试验,其中38株(占28.7%)是异抗性菌株。杂合抗性菌株主要(但不仅限于)发现有第3组噬菌体型菌株。在门诊患者中未发现异抗性菌株。庆大霉素在低浓度下表现出对奥沙西林敏感和耐药菌株的均匀有效药剂。建议在严重葡萄球菌感染的未来临床治疗试验中应将庆大霉素与万古霉素进行比较,特别是在对奥沙西林耐药的菌株引起的情况下。

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