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首页> 外文期刊>Applied Microbiology >Computer Program Designed to Follow Fluctuations in Microbial Populations and Its Application in a Study of Chesapeake Bay Microflora
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Computer Program Designed to Follow Fluctuations in Microbial Populations and Its Application in a Study of Chesapeake Bay Microflora

机译：设计用于跟踪微生物种群波动的计算机程序及其在切塞皮克湾微生物群落研究中的应用

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A computer program has been developed which performs cluster analysis of microorganisms using methods of numerical taxonomy. The program is designed to group related strains, identify the groups by reference to known strains, and calculate a hypothetical median organism (HMO) for each group. The HMO serves to condense taxonomic information and provides a tag for each strain cluster. Every strain in a group is compared with the HMO established for that group. A representative strain for the group is obtained by selection of the strain showing highest similarity to the HMO. New data sets can be compared with data sets of previous analyses. Hence, the occurrence of the same taxonomic groups within separate data sets can be determined. Quantitative or qualitative differences in distribution of taxonomic groups within or between data sets can be measured. The output from the computer is a graphical display, using an on-line plotter; thus, the investigator is provided with visual comparison of data sets. Results obtained from a study applying the computer program in an analysis of taxonomic data obtained for 43 bacterial strains isolated from Chesapeake Bay indicate the usefulness of this method of taxonomic analysis in microbial ecology.
机译：已经开发出一种计算机程序，该计算机程序使用数值分类法对微生物进行聚类分析。该程序旨在对相关菌株进行分组，通过参考已知菌株来识别组，并为每个组计算假设的中位生物（HMO）。 HMO用于浓缩分类信息，并为每个菌株簇提供标签。将组中的每个菌株与为该组建立的HMO进行比较。通过选择与HMO具有最高相似性的菌株来获得该组的代表性菌株。可以将新数据集与先前分析的数据集进行比较。因此，可以确定在单独的数据集中是否存在相同分类组。可以测量数据集内部或数据集之间的分类组分布的数量或质量差异。计算机的输出是使用在线绘图仪的​​图形显示。因此，为调查人员提供了数据集的可视化比较。应用计算机程序对从切萨皮克湾分离的43种细菌菌株分类数据进行分析的研究结果表明，这种分类方法在微生物生态学中很有用。

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