Effects of Actinobolin on Growth and Some Metabolic Activities of Cariogenic Streptococci In Vitro and In Vivo

Bernard B. Keele; Hubert L. Powell; Juan M. Navia; Jerry McGhee

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Effects of Actinobolin on Growth and Some Metabolic Activities of Cariogenic Streptococci In Vitro and In Vivo

机译：肌动蛋白对体内和体内致癌性链球菌生长和某些代谢活性的影响

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Actinobolin, a known inhibitor of protein synthesis, has been shown not to interfere selectively with acid production or dextransucrase activity in a cariogenic streptococcus when the antibiotic is added to a concentration of 500 μg/ml. It has also been shown that actinobolin does not alter the total in vivo flora of the oral cavity of the rat when tested in a rat caries model system. A culture of cariogenic streptococci, adapted to in vitro growth in the presence of 1 mg of actinobolin per ml, has also been isolated.

机译：放线菌素，一种已知的蛋白质合成抑制剂，已显示出当以500μg/ ml的浓度添加抗生素时，不会选择性干扰生龋性链球菌中的产酸或右旋糖核酸酶活性。还已经显示，当在大鼠龋齿模型系统中进行测试时，肌动蛋白不会改变大鼠口腔的总体内菌群。还分离出了致龋性链球菌培养物，该培养物适于在每毫升1毫克放线菌素存在下体外生长。

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《Applied Microbiology》 |1971年第6期|共6页
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Bernard B. Keele; Hubert L. Powell; Juan M. Navia; Jerry McGhee;
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6. Effects of Actinobolin on Growth and Some Metabolic Activities of Cariogenic Streptococci In Vitro and In Vivo [O] . Bernard B. Keele Jr., Hubert L. Powell Jr., Juan M. Navia, 1971

机译：肌动蛋白对体内和体内致癌性链球菌生长和某些代谢活性的影响
7. Effects of Actinobolin on Growth and Some Metabolic Activities of Cariogenic Streptococci In Vitro and In Vivo [O] . Bernard B. Keele, Hubert L. Powell, Juan M. Navia, 1971

机译：Actinobolin对体外和体内致癌链球菌生长和一些代谢活性的影响

Effects of Actinobolin on Growth and Some Metabolic Activities of Cariogenic Streptococci In Vitro and In Vivo

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