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Hemolytic Interaction of Newcastle Disease Virus and Chicken Erythrocytes. II. Determining Factors

机译:新城疫病毒和鸡红细胞的溶血相互作用。二。确定因素

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Standard procedures have been described for measuring paramyxovirus-induced hemolysis. The choice of these procedures is based on the analysis of the behavior of eight different strains of Newcastle disease virus. Significant strain-specific differences in hemolytic activity have been found. The presence of at least two kinds of inhibitors of hemolysis in virus preparations necessitates the use of purified virus when comparisons of hemolytic activities are to be made. In addition, it has been stressed that both hemagglutination titers and hemolysis determinations provide only relative values. Thus, quantitative comparisons can be made only with results obtained on the same day and with the same erythrocyte preparation.
机译:已经描述了用于测量副粘病毒引起的溶血的标准程序。这些程序的选择是基于对八种新城疫病毒株的行为进行分析的。已经发现在溶血活性方面存在明显的菌株特异性差异。当要比较溶血活性时,病毒制剂中至少存在两种​​溶血抑制剂,因此有必要使用纯化的病毒。另外,已经强调的是,血凝滴度和溶血测定均仅提供相对值。因此,只能对同一天和相同的红细胞制备结果进行定量比较。

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