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In Vitro Evaluation of Actinobolin as an Antibiotic for the Treatment of Periodontal Disease

机译:放线菌素作为一种抗生素治疗牙周疾病的体外评价

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Actinobolin was evaluated in vitro by a paper disc-agar diffusion method for inhibitory activity against mixed microbial cultures obtained from patients with periodontal disease and against pure bacterial cultures tentatively identified as strains of Bacteroides melaninogenicus, Fusobacterium fusiforme, Leptotrichia buccalis, and Veillonella parvula. Every culture tested was inhibited to some degree by actinobolin. These observations suggest that actinobolin may be effective in the treatment of periodontal disease.
机译:通过纸碟琼脂扩散法在体外评估放线菌素对从牙周病患者获得的混合微生物培养物的抑制活性,以及​​对初步鉴定为黑色杆菌,梭形Fusobacter fusiforme,丁酸梭状芽胞杆菌和小菜蛾的纯细菌培养物的抑制活性。每种测试的培养物都受到放线菌素的某种程度的抑制。这些观察结果提示放线肌动蛋白可能有效地治疗牙周疾病。

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