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The yctCBA Operon of Yersinia ruckeri, Involved in In Vivo Citrate Uptake, Is Not Required for Virulence

机译:不需要参与毒性柠檬酸的耶尔森氏耶尔森氏菌yctCBA操纵子

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A three-gene operon, named yctCBA ( Y ersinia citrate transporter), induced by citrate and repressed by glucose was identified from a previously selected in vivo -induced ( ivi ) clone in the fish pathogen Yersinia ruckeri . Interestingly, despite being an ivi clone, the drastic growth reduction of the yctC mutant in the presence of citrate, and the relatively high content of this compound in rainbow trout serum, the operon was not required for virulence.
机译:从鱼病原体耶尔森氏菌中先前选择的体内诱导(ivi)克隆中鉴定了由柠檬酸诱导并被葡萄糖抑制的三基因操纵子,称为yctCBA(柠檬酸耶尔森氏菌转运蛋白)。有趣的是,尽管是ivi克隆,在柠檬酸盐存在下yctC突变体的生长急剧减少,并且虹鳟血清中该化合物的含量相对较高,但操纵子并不是毒力所必需的。

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