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Articles of Significant Interest in This Issue

机译:本期重大关注文章

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Organic derivatives of phosphorus-containing acids have a wide range of applications in modern society, but they are in excessive use for the control of agricultural and household pests throughout the world and pose a serious health threat to communities. Getnet et al. (e00978-18) described an altered fecal bacterial biota and urine metabolome that follows intoxication with soman, a lipophilic G class chemical warfare nerve agent, demonstrating that fecal bacterial biota and urine metabolites are two separate biospecimens rich in surrogate indicators suitable for monitoring organophosphorus exposure. Assays developed around these observations can be used to enable better diagnostics and administration of neuroprotective therapies of the future.
机译:含磷的酸的有机衍生物在现代社会中有着广泛的应用,但是在全世界范围内,它们被过量地用于控制农业和家庭害虫,并严重威胁着社区的健康。 Getnet等。 (e00978-18)描述了一种粪便细菌生物群和尿液代谢组的改变,并伴有亲脂性G类化学战神经药剂索曼中毒,证明粪便细菌生物体和尿液代谢物是两个单独的生物标本,富含替代指标,适用于监测有机磷暴露。围绕这些观察结果开发的分析方法可用于更好地诊断和管理未来的神经保护疗法。

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