Characterization of the ars Gene Cluster from Extremely Arsenic-Resistant Microbacterium sp. Strain A33

Asma Achour-Rokbani; Audrey Cordi; Pascal Poupin; Pascale Bauda; Patrick Billard

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Characterization of the ars Gene Cluster from Extremely Arsenic-Resistant Microbacterium sp. Strain A33

机译：极耐砷微细菌sp的ars基因簇的表征。菌株A33

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The arsenic resistance gene cluster of Microbacterium sp. A33 contains a novel pair of genes ( arsTX ) encoding a thioredoxin system that are cotranscribed with an unusual arsRC2 fusion gene, ACR3 , and arsC1 in an operon divergent from arsC3 . The whole ars gene cluster is required to complement an Escherichia coli ars mutant. ArsRC2 negatively regulates the expression of the pentacistronic operon. ArsC1 and ArsC3 are related to thioredoxin-dependent arsenate reductases; however, ArsC3 lacks the two distal catalytic cysteine residues of this class of enzymes.

机译：微小芽孢杆菌的抗砷基因簇。 A33包含一对新的基因（arsTX）编码的硫氧还蛋白系统，与一个不寻常的arsRC2融合基因ACR3和arsC1共转录，其操纵子与arsC3不同。需要完整的ars基因簇来补充大肠杆菌ars突变体。 ArsRC2负调节五顺反子操纵子的表达。 ArsC1和ArsC3与依赖硫氧还蛋白的砷酸还原酶有关。然而，ArsC3缺乏此类酶的两个远端催化半胱氨酸残基。

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《Applied Microbiology》 |2010年第3期|共8页
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Asma Achour-Rokbani; Audrey Cordi; Pascal Poupin; Pascale Bauda; Patrick Billard;
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6. Characterization of the ars Gene Cluster from Extremely Arsenic-Resistant Microbacterium sp. Strain A33 [O] . Asma Achour-Rokbani, Audrey Cordi, Pascal Poupin, 2010

机译：极端抗砷的微细菌sp的ars基因簇的表征。菌株A33
7. Characterization of the ars Gene Cluster from Extremely Arsenic-Resistant Microbacterium sp. Strain A33▿ † [O] . Achour-Rokbani, Asma, Cordi, Audrey, Poupin, Pascal, 2009

机译：极端抗砷的微细菌sp的ars基因簇的表征。菌株A33▿†

Characterization of the ars Gene Cluster from Extremely Arsenic-Resistant Microbacterium sp. Strain A33

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