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Articles of Significant Interest in This Issue

机译：本期重大关注文章

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In order to improve n-butanol synthesis from lignocellulose, natural microbial cells must be extensively modified. Wen et al. (e02560-18) developed genetic tools and a selection protocol for combinatorial metabolic engineering of Clostridium cellulovorans into a promising n-butanol fermentation chassis from lignocellulose by consolidated bioprocessing. The n-butanol production increased further under a two-stage pH control strategy.Most defined systems have identified microbial elements as the primary factors determining disease suppression, but the involvement of the soil abiotic environment is less defined. Studies in a reductive soil disinfestation-managed disease-suppressive soil by Liu et al. (e02992-18) showed that the soil abiotic environment played a critical role in the establishment of the soil microbial community and key microbial agents that directly contributed to the prevention of soil-borne diseases. These results highlight the important but indirect effect of the soil abiotic environment on disease suppression.
机译：为了改善从木质纤维素合成正丁醇，必须对天然微生物细胞进行大量修饰。 Wen等。 （e02560-18）开发了遗传工具和用于将梭状芽胞杆菌组合代谢工程化为通过有前途的生物处理从木质纤维素转化为有前途的正丁醇发酵底盘的遗传选择工具。在两阶段的pH控制策略下，正丁醇的产量进一步增加，大多数确定的系统已将微生物元素确定为决定疾病抑制的主要因素，但对土壤非生物环境的参与却知之甚少。 Liu等在还原性土壤除虫管理的疾病抑制土壤中的研究。 （e02992-18）表明，土壤非生物环境在建立土壤微生物群落和直接促进土壤传播疾病预防的关键微生物制剂的建立中发挥了关键作用。这些结果突出了土壤非生物环境对疾病抑制的重要但间接的影响。

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