Bringing the parts together: Steps towards an in-silico protocell

Eugenia Schneider; Jakob Schweizer; Michael Mangold

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Bringing the parts together: Steps towards an in-silico protocell

机译：将各个部分放在一起：迈向硅内原型电池

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Abstract: This article focuses on a system theoretic approach to synthetic biology, and in particular on the construction of a protocell model. The questions addressed here are: Which parts of functional modules are required to describe a protocell and which design methods are needed for self-replicating systems. We describe a model for an in-silico protocell that combines experimentally validated biological subsystems with theoretical studies.

机译：摘要：本文主要关注合成生物学的系统理论方法，尤其是原始细胞模型的构建。这里解决的问题是：描述一个原型单元需要功能模块的哪些部分，以及自我复制系统需要哪些设计方法。我们描述了一个硅内原始细胞模型，该模型结合了经过实验验证的生物学子系统和理论研究。

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《IFAC PapersOnLine》 |2016年第26期|共6页
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Eugenia Schneider; Jakob Schweizer; Michael Mangold;
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中图分类自动化技术、计算机技术;
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专利

1. Modular assembling process of an in-silico protocell [J] . Schneider Eugenia, Mangold Michael BioSystems . 2018,第期

机译：In-Silico Protocell的模块化组装过程
2. Steps Towards the Formation of A Protocell: The Possible Role of Short Peptides [J] . Maya Fishkis Origins of Life and Evolution of Biospheres . 2007,第6期

机译：形成原细胞的步骤：短肽的可能作用
3. In-silico cell surface modeling reveals mechanism for initial steps of B-cell receptor signal transduction. [J] . Nudelman G, Weigert M, Louzoun Y Molecular Immunology . 2009,第15期

机译：硅细胞表面建模揭示了B细胞受体信号转导初始步骤的机制。
4. Bringing the parts together: Steps towards an in-silico protocell [C] . Eugenia Schneider, Jakob Schweizer, Michael Mangold IFAC Conference on Foundations of Systems Biology in Engineering . 2017

机译：将零件一起带来：迈向硅片的步骤
5. Towards the construction of synthetic protocells: Engineering responsive polymer membranes. [D] . Kamat, Neha Prashant. 2012

机译：迈向合成原始细胞的构建：工程响应性聚合物膜。
6. A Self-Assembled Aggregate Composed of a Fatty Acid Membrane and the Building Blocks of Biological Polymers Provides a First Step in the Emergence of Protocells [O] . Roy A. Black, Matthew C. Blosser 2016

机译：由脂肪酸膜和生物聚合物的结构单元组成的自组装聚集体提供了原生细胞的第一步
7. Preliminary steps toward artificial protocell computation [O] . McMullin Barry, Kelly Ciarán, OBrien Darragh, 2007

机译：人工原始细胞计算的初步步骤
8. Procurement and Use of Medicines in Afghanistan: An Interim Report on the steps taken by the Republic of Afghanistan Ministry of Public Health to bring low-cost, Quality drugs to it's people [R] . 1974

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Bringing the parts together: Steps towards an in-silico protocell

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