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Immune Responses in Infections with Coccidia: Macrophage Activity

机译:球菌感染的免疫反应:巨噬细胞活性。

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Peritoneal exudate cells from chickens immunized with two species of coccidia, Eimeria tenella or Eimeria maxima, were examined for their capacity to phagocytose stages of the parasite in vitro. True phagocytosis of the sporozoite stage is difficult to estimate because of its ability to invade cells, but may be evaluated by comparison with control suspensions. Peak activity (compared with cells from coccidia-free chickens) was found 3 to 5 weeks after the first inoulum of oocysts of E. tenella, and 1 week after the first inoculum of E. maxima— times which correspond to the onset of complete immunity to infection. Cells from coccidia-free chickens, in the presence of serum from birds immunized with E. tenella, phagocytosed sporozoites of E. tenella in a similar manner to cells from immunized birds. The immune serum had both cytophilic and opsonic adherence properties and the latter was species specific (for the two species tested).
机译:检查了用两种球菌 Eimeria tenella Eimeria maxima 免疫的鸡的腹膜分泌液在体外吞噬寄生虫的能力。子孢子阶段的真正吞噬作用由于其入侵细胞的能力而难以估计,但可以通过与对照悬浮液比较来评估。在 E卵囊的第一个灌入后3至5周发现了峰值活性(与不含球虫的鸡的细胞相比)。 Tenella ,以及 E的第一个接种物后1周。最大值-与感染完全免疫开始的时间相对应。在用 E免疫的鸟类的血清中,从无球虫的鸡中得到细胞。 tenella ,吞噬了 E的子孢子。 Tenella 的方式类似于免疫鸟类的细胞。免疫血清同时具有嗜细胞和调理作用的粘附特性,后者是物种特异的(对于测试的两个物种)。

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