• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Infection and immunity >Influence of cell type and virus upon virus-specific immune cytolysis.
【24h】

Influence of cell type and virus upon virus-specific immune cytolysis.

机译：细胞类型和病毒对病毒特异性免疫细胞溶解的影响。

获取原文
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Immune cytolysis was measured by release of absorbed radioactive chromium from infected cells that were incubated with antiviral antibody and complement. The presence of virus-specific antigens detected in this manner on the surface of several types of cells infected with Japanese encephalitis (JE) virus did not correlate in each instance with the maturation of infectious virus. JE-infected LLC-MK-2 and Vero cells could not be lysed until long after the first appearance of released virus, and the lysis was minimal in that only a small amount of chromium was released. However, JE-infected BHK-21 and chicken embryo cells could be lysed as soon as new virus was detected in the culture medium, and the lysis reached maximum levels before the time that maximum levels of infectious virus were found in the culture fluids. This phenomenon was restricted to JE virus since BHK-21 cells infected with dengue-2 virus (another group B arbovirus) could not be lysed until well after the appearance of new virus in the culture medium.
机译：通过从与抗病毒抗体和补体孵育的感染细胞中释放吸收的放射性铬来测量免疫细胞溶解。以这种方式检测到的感染日本脑炎（JE）病毒的几种类型细胞表面上存在的病毒特异性抗原在每种情况下均与传染性病毒的成熟无关。被JE感染的LLC-MK-2和Vero细胞要等到首次出现释放的病毒后很长时间才能被裂解，并且裂解极少，因为只有少量的铬被释放。但是，一旦在培养基中检测到新病毒，就可以裂解JE感染的BHK-21和鸡胚细胞，并且在培养液中发现最大感染性病毒之前，裂解达到最大水平。这种现象仅限于JE病毒，因为感染登革2病毒的BHK-21细胞（另一种B组虫媒病毒）要等到新病毒在培养基中出现后才能溶解。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号