Role of Zinc in the Production of Clostridium perfringens Alpha Toxin

Hiroko Sato; Ryosuke Murata

首页> 外文期刊>Infection and immunity >Role of Zinc in the Production of Clostridium perfringens Alpha Toxin

【24h】

Role of Zinc in the Production of Clostridium perfringens Alpha Toxin

机译：锌在产气荚膜梭菌α毒素生产中的作用

获取原文

掌桥外文数据库（机构版） >>

开具论文收录证明 >>

文献代查 >>

页面导航

摘要
著录项
相似文献
相关主题

摘要

Clostridium perfringens was found to produce alpha toxin in a synthetic medium containing zinc; in medium containing no zinc, a little toxin was detected in the early logarithmic phase of growth and it disappeared rapidly. No intracellular accumulation of alpha toxin protein occurred whether or not zinc was present in the medium. In zinc-deficient medium, the organisms produced and released into the surrounding medium the protein specifically precipitable with alpha antitoxin in an amount comparable to that of alpha toxin produced in the zinc-containing medium. The protein combined rapidly in some unknown way with zinc to form the active and stable alpha toxin.

机译：发现产气荚膜梭菌在含锌的合成培养基中产生α毒素。在不含锌的培养基中，在对数生长的早期阶段检测到少量毒素，并且毒素迅速消失。无论培养基中是否存在锌，都不会发生α毒素蛋白的细胞内积累。在缺锌培养基中，生物体产生的蛋白质被α抗毒素特异性沉淀，然后释放到周围的介质中，其数量与含锌培养基中产生的α毒素相当。该蛋白质以某种未知的方式与锌迅速结合，形成了活性和稳定的α毒素。 展开▼

著录项

来源
《Infection and immunity》 |1973年第3期|共10页

作者
Hiroko Sato; Ryosuke Murata;
展开▼

作者单位

展开▼

收录信息

原文格式 PDF

正文语种

中图分类医学免疫学;

关键词

相似文献

外文文献

中文文献

专利

1. Dynamics of plc gene transcription and alpha-toxin production during growth of Clostridium perfringens strains with contrasting alpha-toxin production. [J] . Veterinary Microbiology . 2009,第1a2期

机译：产气荚膜梭状芽孢杆菌菌株生长过程中plc基因转录和α-毒素产生的动态与α-毒素产生的对比。

2. Effect of zinc and calcium ions on the production of alpha-toxin and proteases by Clostridium perfringens. [J] . H Sato, Y Yamakawa, A Ito, Infection and immunity . 1978,第2期

机译：锌和钙离子对产气荚膜梭菌产生α-毒素和蛋白酶的影响。

3. The inhibition of lipopolysaccharide-induced tumor necrosis factor-alpha and nitric oxide production by Clostridium perfringens alpha-toxin and its relation to alpha-toxin-induced intracellular ceramide generation (vol 299, pg 554, 2009) [J] . Tumurkhuu Gantsetseg, Koide Naoki, Dagvadorj Jargalsaikhan, International journal of medical microbiology: IJMM . 2015,第3期

机译：产气荚膜梭菌α毒素抑制脂多糖诱导的肿瘤坏死因子α和一氧化氮的产生及其与α毒素诱导的细胞内神经酰胺生成的关系（第299卷，第554页，2009）

4. Evaluation of the Ability of Di-tri-octahedral Smectite to Adhere to Clostridium difficile Toxins and Clostridium perfringens Enterotoxin In Vitro [C] . J. S. Weese, N. M. Cote, R. V. G. deGannes Annual Convention of the American Association of Equine Practitioners . 2002

机译：评价Di-Tri-octaheDral蒙脱石粘附到梭菌腹菌毒素和梭菌梭菌中的能力

5. QUANTIFICATION AND SELECTED PROPERTIES OF ALPHA TOXIN OF CLOSTRIDIUM PERFRINGENS [D] . PARK, YOONG. -1

机译：环孢梭菌α-毒素的定量及选择性能

6. Role of Zinc in the Production of Clostridium perfringens Alpha Toxin [O] . Hiroko Sato, Ryosuke Murata 1973

机译：锌在产气荚膜梭菌α毒素生产中的作用

7. Role of Zinc in the Production of Clostridium perfringens Alpha Toxin [O] . Hiroko Sato, Ryosuke Murata 1973

机译：锌在生产梭菌梭菌中的作用

8. Quantitative Electrochemiluminescence Assay for Clostridium perfringens alpha toxin [R] . Merrill, G. A. , Rivera, V. R. , Neal, D. D. , 2006

机译：产气荚膜梭菌α毒素的定量电化学发光分析

1. 仔猪产气荚膜梭菌肠毒血症病原诊断及疫苗研究Ⅲ.7株A型产气荚膜梭菌菌株的产毒素试验 [J] . 屠伟英 ,蒋玉文 ,蔡祈英 . 中国兽药杂志 . 2003,第008期

2. 产气荚膜梭菌重组NetB毒素细胞毒性作用研究 [J] . 王莹莹 ,乔艺然 ,赵蕾 . 畜牧兽医学报 . 2016,第005期

3. D型产气荚膜梭菌ε毒素基因表达及其免疫保护作用的初步研究 [J] . 王光华 ,蔺国珍 ,郑福英 . 中国畜牧兽医 . 2012,第003期

4. A型产气荚膜梭菌α毒素基因表达及其免疫保护作用的初步研究 [J] . 许崇波 ,许崇利 ,赵志军 . 微生物学报 . 2006,第004期

5. 重组A型产气荚膜梭菌α毒素保护性抗原的制备及初步免疫保护作用研究 [J] . 林明辉 ,荫俊 ,邢洪光 . 生物工程学报 . 2004,第001期

6. 抗产气荚膜梭菌β毒素IgG的纯化与β毒素Dot-ELISA测定方法的研究 [C] . 张存帅 ,薛民权 . 北京微生物学会青年科技创新论坛报告会 . 1999

7. 我国部分地区蛋鸡产气荚膜梭菌毒素型调查及恩拉霉素对产气荚膜梭菌抑菌作用研究 [A] . 王浩 . 2013

1. 一种无毒性破伤风毒素和产气荚膜梭菌β毒素重组融合蛋白 [P] . 中国专利： CN109942718B . 2020.12.25

2. 一种无毒性的产气荚膜梭菌重组ε毒素和α毒素融合蛋白疫苗及其生产方法 [P] . 中国专利： CN109745554A . 2019-05-14

3. Nucleic acid molecule encoding a substantially non-toxic mutein of clostridium perfringens alpha-toxin and attenuated clostridium perfringens organisms comprising said nucleic acid [P] . 外国专利： IL194714A . 2015-03-31

机译：编码基本上无毒的产气荚膜梭菌α毒素的突变蛋白和减毒的产气荚膜梭菌生物的核酸分子

4. Nucleic Acid encoding a muteina of alpha toxin of Clostridium perfringens; such muteina; C.Vaccine comprising Said attenuated perfringens; microorganism; use of vaccine to induce Immunity against C. perfringens. [P] . 外国专利： CL2007001071A1 . 2007-09-28

机译：编码产气荚膜梭状芽孢杆菌α毒素突变体的核酸;这样的静音C.疫苗，包括所述减毒的产气荚膜毒素;微生物;使用疫苗诱导产气荚膜梭菌免疫。

5. A B E alpha Method for detecting rapidly botulium toxin A B E and Clostridium perfringens alpha toxin and detection kit [P] . 外国专利： KR101823353B1 . 2018-01-31

机译：快速检测肉毒杆菌毒素的A B E alpha方法A B E和产气荚膜梭菌α毒素和检测试剂盒

相关主题

Role of Zinc in the Production of Clostridium perfringens Alpha Toxin

摘要

著录项

相似文献

相关主题

期刊订阅