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Immunodiffusion Studies of Purified Equine Infectious Anemia Virus

机译：纯化马传染性贫血病毒的免疫扩散研究

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Antigenicity of purified equine infectious anemia (EIA) virus was examined by immunodiffusion against sera obtained from horses experimentally infected with EIA virus. The purified virus reacted with the infected horse serum, and virus-specific precipitating antibody was demonstrated. Furthermore, it was found that purified EIA virus reacted against the serum of horses infected with all strains of EIA virus which were antigenically different from one another. From the result, group-specific components of the virus rather than strain-specific ones were considered to be involved in the reaction. Serological reactivity was lost by adding antiserum from the infected horse to the antigen. The precipitating antibody usually appeared in the serum 1 to 2 weeks after the first febrile attack of EIA and remained for a longer period. Some characteristics of the purified antigen and specificity of the reaction for EIA are described.
机译：通过针对从实验感染EIA病毒的马中获得的血清进行免疫扩散，检查了纯化的马传染性贫血（EIA）病毒的抗原性。纯化的病毒与受感染的马血清反应，并证明了病毒特异性沉淀抗体。此外，发现纯化的EIA病毒与感染了彼此抗原性不同的所有EIA病毒株的马的血清反应。从结果来看，该病毒的组特异性成分而非菌株特异性成分被认为与反应有关。通过将来自感染马的抗血清添加到抗原中来丧失血清反应性。沉淀的抗体通常在EIA第一次发热发作后1至2周出现在血清中，并保持更长的时间。描述了纯化抗原的一些特征和对EIA的反应特异性。

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