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Antitumor activity of a Brucella abortus preparation.

机译:流产布鲁氏菌制剂的抗肿瘤活性。

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Mice injected intraperitoneally with sarcoma-180 cells develop ascites and eventually die. Intraperitoneal injection of a nonviable, aqueous... ether-extracted Brucella abortus preparation (BRU-PEL) as early as 7 days before or as late as 7 days after injection of tumor cells significantly inhibited development of ascites and protected against death. BRU-PEL was not effective if injected after ascites was grossly apparent. BRU-PEL was significantly more active than a Corynebacterium parvum preparation administered in the same way.
机译:腹膜内注射肉瘤180细胞的小鼠腹水并最终死亡。早在腹腔注射瘤细胞前7天或腹腔注射腹腔注射乙醚提取的布鲁氏菌流产制剂(BRU-PEL)即可显着抑制腹水的形成并防止死亡。如果在明显出现腹水后注射BRU-PEL无效。 BRU-PEL的活性明显高于以相同方式施用的小棒杆菌制剂。

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