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Vero response to a cytotoxin of Escherichia coli.

机译:Vero对大肠杆菌细胞毒素的反应。

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A cytotoxin was found in culture filtrates of a number of Escherichia coli strains that differed from the known heat-stable and heat-labile enterotoxins of E. coli. It was cytotoxic for Vero but not for Y-1 or CHO cells, and its effect on Vero was distinctly different from that of heat-labile enterotoxin. It was labile to heat and antigenically different from heat-labile enterotoxin, and membrane filtration indicated a molecular weight of 10,000 to 30,000.
机译:在许多大肠杆菌菌株的培养滤液中发现了一种细胞毒素,该菌株不同于已知的大肠杆菌的热稳定和热不稳定的肠毒素。它对Vero具有细胞毒性,但对Y-1或CHO细胞无毒,并且对Vero的作用与热不稳定肠毒素的作用明显不同。它不易加热,抗原性不同于不耐热肠毒素,膜过滤表明分子量为10,000至30,000。

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