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Immunogenicity of R Factor-Carrying Salmonella

机译:携带R因子的沙门氏菌的免疫原性

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An increased frequency of rough cultures with associated reductions in mouse virulence was detected after R-factor transmission into strains of Salmonella choleraesuis var. kunzendorf and S. typhimurium. All rough strains tested, with or without R factors, conferred protective immunity against challenge with homologous or heterologous species of Salmonella, some of which contained R factors. Although slight protection was afforded against challenge with Staphylococcus aureus, the immunity was specific to the extent that immunized mice were fully susceptible to infections with Klebsiella pneumoniae and Pasteurella multocida.
机译:R因子传播到霍乱沙门氏菌 var株中后,毛坯培养的频率增加,鼠毒性降低。 kunzendorf S。鼠伤寒。所有测试的粗菌株,不论是否具有R因子,均能抵抗沙门氏菌的同源或异源物种(其中一些包含R因子)的攻击性的保护性免疫力。尽管对金黄色葡萄球菌的攻击提供了轻微的保护,但这种免疫是特异性的,免疫小鼠对肺炎克雷伯菌和多杀性巴斯德氏菌完全敏感。

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