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Post-Transfusion Cytomegaloviremia and Persistence of Cytomegalovirus in Blood

机译：输血后巨细胞病毒血症和血液中巨细胞病毒的持续存在

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Cytomegaloviremia was documented in seven patients. Three patients were renal transplant recipients and two were liver transplant recipients. One was a postcardiac surgery patient, and one had acute myelogenous leukemia. The transplant patients had received only banked blood or fresh frozen plasma and developed evidence of infection about 1 month after surgery. Illness varied from no apparent signs to fever alone, fever and a morbilliform rash, hepatitis and an infectious mononucleosis syndrome. The virus was isolated from the blood erythrocyte layer, the leukocyte layer, and the plasma and serum, in that order of frequency. In vitro studies demonstrated persistence of inoculated cytomegalovirus in the presence of erythrocytes (and tissue culture media) for up to 21 days. In whole blood under banking conditions, inoculated virus was recovered after 28 days and, in fresh frozen plasma, after 97 days.
机译：已有七例患者发生巨细胞病毒血症。三名患者是肾移植受者，两名是肝移植受者。一名是明信片外科手术患者，一名患有急性骨髓性白血病。移植患者仅接受了储备的血液或新鲜的冷冻血浆，并在术后约1个月出现了感染迹象。疾病的范围从无明显迹象到单独发烧，发烧和丝状皮疹，肝炎和传染性单核细胞增多症。以该频率顺序从血液红细胞层，白细胞层以及血浆和血清中分离出病毒。体外研究表明，在存在红细胞（和组织培养基）的情况下，接种巨细胞病毒的持续时间长达21天。在银行条件下的全血中，接种的病毒在28天后恢复，而在新鲜的冷冻血浆中则在97天后恢复。

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