Multiplicity of Scrapie Virus in Infected Mouse Spleen Cells In Vivo

G. C. Lavelle

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Multiplicity of Scrapie Virus in Infected Mouse Spleen Cells In Vivo

机译：体内感染的小鼠脾脏细胞中的Sc痒病毒的多样性

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Subpopulations of spleen cells from scrapie virus-infected mice were used to determine the average virus content of infected cells in vivo at a time when virus was rapidly increasing in titer in lymphoreticular tissues. Comparison of the mean lethal doses of lysed to intact cells indicated averages of 2 to 6 infectious units per infected cell. In another experiment, preparations of cytoplasmic nucleic acids extracted from spleen cells of infected mice had no detectable infectivity, which suggests that the transmissible form of the virus is not a free nucleic acid.

机译：当病毒在淋巴网状组织中的滴度迅速增加时，使用刮伤病毒感染小鼠的脾细胞亚群来确定体内感染细胞的平均病毒含量。对完整细胞裂解的平均致死剂量的比较表明每个感染细胞平均2至6个感染单位。在另一个实验中，从受感染小鼠脾细胞中提取的细胞质核酸制剂没有可检测的感染性，这表明病毒的可传播形式不是游离核酸。

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《Infection and immunity》 |1973年第6期|共4页
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G. C. Lavelle;
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1. Isolation from Mouse Spleen of Cell Populations with High Specific Infectivity for Scrapie Virus [J] . G. C. Lavelle, L. Sturman, W. J. Hadlow Infection and immunity . 1972,第3期

机译：从鼠脾中分离出具有高特异性感染性的爬虫病毒细胞群
2. Accumulation of Cholesterol Esters in ex vivo Lymphocytes from Scrapie-susceptible Sheep and in Scrapie-infected Mouse Neuroblastoma Cell Lines [J] . Alessandra Pani, Claudia Norfo, Claudia Abete, American journal of infectious diseases. . 2007,第3期

机译：易感染绵羊的离体淋巴细胞中和胆固醇感染的小鼠神经母细胞瘤细胞系中胆固醇酯的积累
3. In vitro culture of coxsackievirus group B, type 3 immune spleen cells on infected endothelial cells and biological activity of the cultured cells in vivo. [J] . S A Huber, L P Job, J F Woodruff Infection and immunity . 1984,第2期

机译：柯萨奇病毒B组，感染的内皮细胞上的3型免疫脾细胞的体外培养以及体内培养的细胞的生物学活性。
4. Expression and characterization of mouse epidermal transglutaminase in baculovirus-infected insect cells [C] . Kiyotaka Hitomi, Koji Ikura, Masatoshi Maki Joint International Meeting of the Japanese Association for Animal Cell Technolog and and European Society for Animal Cell Technology . 1999

机译：小鼠表皮转谷氨酰胺酶在杆状病毒感染昆虫细胞中的表达及表征
5. Analysis of the transcription of immediate early regulatory genes of Varicella-Zoster virus and host cell gene expression in VZV-infected cells in vitro and in the SCIDhu mouse model in vivo. [D] . Jones, Jeremy Orion. 2005

机译：水痘带状疱疹病毒的早期早期调控基因的转录和体外感染VZV的细胞以及体内SCIDhu小鼠模型中宿主细胞基因表达的分析。
6. Multiplicity of Scrapie Virus in Infected Mouse Spleen Cells In Vivo [O] . G. C. Lavelle 1973

机译：体内感染的小鼠脾脏细胞中的爬虫病毒多样性
7. Multiplicity of Scrapie Virus in Infected Mouse Spleen Cells In Vivo [O] . G. C. Lavelle 1973

机译：在体内感染的小鼠脾细胞中的氟斯病毒多样性
8. Blastogenic Response of 'Toxoplasma'-Infected Mouse Spleen Cells to T- and B-Cell Mitogens. [R] . Strickland, G. T., Ahmed, A., Sell, K. W. 1975

机译：'弓形虫'感染的小鼠脾细胞对T细胞和B细胞mitogens的爆发性反应。

Multiplicity of Scrapie Virus in Infected Mouse Spleen Cells In Vivo

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