Delayed-type hypersensitivity to rabies virus in mice: assay of active or passive sensitization by the footpad test.

P H Lagrange; H Tsiang; B Hurtrel; P Ravisse

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Delayed-type hypersensitivity to rabies virus in mice: assay of active or passive sensitization by the footpad test.

机译：小鼠对狂犬病毒的迟发型超敏反应：通过脚垫试验测定主动或被动致敏作用。

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With a purified beta-propiolactone-inactivated rabies virus, a significant increase in footpad swelling was elicited in normal or in BCG-pretreated mice after immunization with varying doses of rabies vaccine. These footpad reactions were shown to peak at 24 h and to be associated with an infiltration of newly formed blood monocytes demonstrated by histology and [125I]deoxyuridine labeling. A relationship between the lymphoproliferation and the degree of sensitization is described, and the susceptibility to cyclophosphamide treatment is also examined. Adoptive transfer of specific reactivity to normal recipient mice with immune lymphoid cells, but not with immune serum, was demonstrated, and the results represent another argument for a cell-mediated immunological mechanism.

机译：使用纯化的β-丙内酯灭活的狂犬病病毒，在用不同剂量的狂犬病疫苗免疫后，正常小鼠或BCG预处理的小鼠的足垫肿胀明显增加。这些脚垫反应显示在24小时达到峰值，并与组织学和[125I]脱氧尿苷标记表明的新形成的血液单核细胞浸润有关。描述了淋巴细胞增殖与敏化程度之间的关系，还研究了对环磷酰胺治疗的敏感性。已经证明了特异性反应性向具有免疫淋巴样细胞而非免疫血清的正常受体小鼠的过继转移，并且该结果代表了细胞介导的免疫机制的另一个论点。

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《Infection and immunity》 |1978年第3期|共9页
作者
P H Lagrange; H Tsiang; B Hurtrel; P Ravisse;
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中图分类医学免疫学;
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1. Delayed-type hypersensitivity to influenza virus. Induction of antigen-specific suppressor T cells for delayed-type hypersensitivity to hemagglutinin during influenza virus infection in mice. [J] . F Y Liew, S M Russell The Journal of Experomental Medicine . 1980,第4期

机译：对流感病毒的迟发型超敏反应。诱导抗原特异性抑制性T细胞在小鼠流感病毒感染期间对血凝素的迟发型超敏反应。
2. Genetic regulation of delayed-type hypersensitivity responses to poly(LTyr,LGlu)-poly(DLAla)--poly(LLys). II. Evidence for a T-T-cell collaboration in delayed-type hypersensitivity responses and for a T-cell defect at the efferent phase in nonresponder H-2k mice. [J] . G Strassmann, Z Eshhar, E Mozes The Journal of Experomental Medicine . 1980,第3期

机译：对聚（LTyr，LGlu）-聚（DLAla）-聚（LLys）的迟发型超敏反应的遗传调控。二。在无反应性H-2k小鼠中，迟发型超敏反应中的T-T细胞协同作用以及传出期T细胞缺陷的证据。
3. Topical azithromycin and clarithromycin inhibit acute and chronic skin inflammation in sensitized mice, with apparent selectivity for Th2-mediated processes in delayed-type hypersensitivity. [J] . Vanesa Iveti? Tkal?evi?, Snje?ana Cu?i?, Miroslava Dominis Kramari?, Inflammation . 2012,第1期

机译：局部用阿奇霉素和克拉霉素可抑制致敏小鼠的急性和慢性皮肤炎症，在延迟型超敏反应中对Th2介导的过程具有明显的选择性。
4. Inflammatory Responses in the Nervous System of Mice Infected with a Street Isolate of Rabies Virus [C] . N. Johnson, K.L Mansfield, D. Hicks, Joint World Organisation for Animal Health/World Health Organization/European Union International Conference "Towards the elimination of rabies in Eurasia" . 2008

机译：用狂犬病病毒的街头孤立感染小鼠神经系统中的炎症反应
5. Modulation of delayed-type hypersensitivity in mice during infection with Trichinella pseudospiralis or Trichinella spiralis. [D] . Kennedy, Rebecca Ruth. 1989

机译：小鼠旋毛虫或旋毛虫感染期间迟发型超敏反应的调节。
6. Delayed-type hypersensitivity to rabies virus in mice: assay of active or passive sensitization by the footpad test. [O] . P H Lagrange, H Tsiang, B Hurtrel, 1978

机译：小鼠对狂犬病毒的迟发型超敏反应：通过脚垫试验进行主动或被动致敏试验。
7. Delayed-Type Hypersensitivity (DTH) Response to Dengue Virus in Mice: Effect of Route of Sensitization and Splenectomy [O] . Tikki Pang, Kok Leong Yap, Shamala Devi, 1983

机译：延迟型超敏反应（DTH）对小鼠登革热病毒的反应：敏化和脾切除术的影响

Delayed-type hypersensitivity to rabies virus in mice: assay of active or passive sensitization by the footpad test.

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