Requirements for fatty acid synthesis and a chelation-sensitive step in the production of glucosyltransferase by Streptococcus mutans.

H K Kuramitsu; L Wondrack

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Requirements for fatty acid synthesis and a chelation-sensitive step in the production of glucosyltransferase by Streptococcus mutans.

机译：变形链球菌生产葡萄糖基转移酶中脂肪酸合成和螯合敏感步骤的要求。

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The antibiotic cerulenin differentially inhibited the production of glucosyltransferase activity by Streptococcus mutans GS5. Cerulenin preferentially inhibited [14C]acetate incorporation into cellular lipids but did not affect protein synthesis or ribonucleic acid synthesis in the same manner. No significant intracellular accumulation of glucosyltransferase activity could be demonstrated in cultures treated with cerulenin. On the other hand, another inhibitor of lipid synthesis, sodium chlorophenoxyisobutyrate, did not differentially inhibit glucosyltransferase expression. In addition, the role of a metal-requiring protease in the production of glucosyltransferase activity was suggested by the observation that the chelator quinacrine differentially inhibited the production of the enzyme.

机译：抗生素铜蓝蛋白差异性地抑制了变形链球菌GS5产生的葡萄糖基转移酶活性。鹰嘴豆素优先抑制[14C]乙酸酯掺入细胞脂质中，但不以相同方式影响蛋白质合成或核糖核酸合成。在用铜蓝素处理的培养物中，未显示出葡萄糖基转移酶活性的明显细胞内积累。另一方面，脂质合成的另一种抑制剂，氯苯氧基异丁酸钠没有差异性地抑制葡糖基转移酶的表达。另外，通过观察到螯合剂奎纳克林差异地抑制了酶的产生，表明了一种需要金属的蛋白酶在葡萄糖基转移酶活性产生中的作用。

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《Infection and immunity》 |1980年第1期|共6页
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H K Kuramitsu; L Wondrack;
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1. Production, characterization, and application of monoclonal antibodies which distinguish three glucosyltransferases from Streptococcus mutans. [J] . K Fukushima, T Okada, K Ochiai Infection and immunity . 1993,第1期

机译：区分三种葡糖基转移酶和变形链球菌的单克隆抗体的生产，表征和应用。
2. Effect of Tween 80 on glucosyltransferase production in Streptococcus mutans. [J] . Y Umesaki, Y Kawai, M Mutai Applied and Environmental Microbiology . 1977,第2期

机译：吐温80对变形链球菌中葡糖基转移酶产生的影响。
3. Regulation and extracellular glucosyltransferase production and the relationship between extracellular and cell-associated activities in Streptococcus mutans. [J] . W M Janda, H K Kuramitsu Infection and immunity . 1976,第1期

机译：变形链球菌的调节和细胞外葡萄糖基转移酶的产生以及细胞外和细胞相关活性之间的关系。
4. Effect of MgO to Fatty Acid Molar Ratio on the Production of Magnesium Salt of Fatty Acid from Palm Fatty Acid Distillates (PFAD) for Food Additives [C] . Listianingrum, Reni Yuniarti, Rd.H.R.M.T. Al-Aziz, International Joint Conference on Advanced Engineering and Technology . 2018

机译：MgO对脂肪酸摩尔比对食品添加剂（PFAD）脂肪酸镁盐生产的影响
5. Role of Aminotransferases in Branched-Chain Amino Acid Metabolism: Acid Tolerance and Fatty Acid Synthesis in Streptococcus mutans. [D] . Santiago, Brendaliz. 2012

机译：氨基转移酶在支链氨基酸代谢中的作用：变形链球菌的耐酸性和脂肪酸合成。
6. Requirements for fatty acid synthesis and a chelation-sensitive step in the production of glucosyltransferase by Streptococcus mutans. [O] . H K Kuramitsu, L Wondrack 1980

机译：变形链球菌生产葡萄糖基转移酶中脂肪酸合成和螯合敏感步骤的要求。
7. Multi-Step Enzymatic Synthesis of 1,9-Nonanedioic Acid from a Renewable Fatty Acid and Its Application for the Enzymatic Production of Biopolyesters [O] . Chae-Yun Kim, Young-Seo Kang, Eun-Ji Seo, 2019

机译：来自可再生脂肪酸的1,9-壬二酸的多步酶合成及其在酶促酶的酶促生产中的应用

Requirements for fatty acid synthesis and a chelation-sensitive step in the production of glucosyltransferase by Streptococcus mutans.

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