Genetic control of natural immunity to ecotropic mouse leukemia viruses: immune response genes.

R C Nowinski

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Genetic control of natural immunity to ecotropic mouse leukemia viruses: immune response genes.

机译：对嗜交性小鼠白血病病毒天然免疫力的遗传控制：免疫应答基因。

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Humoral immune response to ectropic leukemia viruses in AKR and C57BL/6 mice was controlled by a gene that mapped in linkage group IX. Mice of the AKR strain had an immune nonresponsive allele of this gene, whereas mice of the C57BL/6 strain had an immune responsive allele. Antibody against murine leukemia virus (MuLV) reacted primarily with p15 protein of the viral envelope. It was concluded that the failure to find antibody production in AKR mice was the result of a genetic immunological defect, rather than the result of immunological tolerance that was induced by the persistent viremia of endogenous MuLV.

机译：AKR和C57BL / 6小鼠对异型白血病病毒的体液免疫反应受IX组连锁基因的调控。 AKR株的小鼠具有该基因的免疫无应答等位基因，而C57BL / 6株的小鼠具有免疫应答的等位基因。鼠白血病病毒（MuLV）抗体主要与病毒包膜的p15蛋白反应。结论是，未能在AKR小鼠中找到抗体的产生是遗传免疫学缺陷的结果，而不是内源性MuLV持续病毒血症引起的免疫耐受性的结果。

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《Infection and immunity》 |1976年第4期|共5页
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R C Nowinski;
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中图分类医学免疫学;
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1. Genetic control of natural immunity to ecotropic mouse leukemia viruses: production of endogenous immunogen. [J] . R C Nowinski, S L Kaehler, J Baron Infection and immunity . 1976,第4期

机译：对嗜交性小鼠白血病病毒天然免疫力的遗传控制：产生内源性免疫原。
2. Genetic control of T cell responsiveness to the Friend murine leukemia virus envelope antigen. Identification of class II loci of the H-2 as immune response genes. [J] . M Miyazawa, J Nishio, B Chesebro The Journal of Experomental Medicine . 1988,第5期

机译：T细胞对Friend鼠白血病病毒包膜抗原反应性的遗传控制。鉴定H-2的II类基因座为免疫反应基因。
3. Sulforaphane promotes immune responses in a WEHI-3-induced leukemia mouse model through enhanced phagocytosis of macrophages and natural killer cell activities in vivo [J] . Shih Yung-Luen, Wu Lung-Yuan, Lee Ching-Hsiao, Molecular medicine reports . 2016,第5aPta1期

机译：萝卜硫素通过增强巨噬细胞的吞噬作用和体内自然杀伤细胞的活性来促进WEHI-3诱导的白血病小鼠模型的免疫反应
4. A Complex Mathematical Model with Competition in Leukemia with Immune Response - An Optimal Control Approach [C] . I.R. Radulescu, D. Candea, A. Halanay IFIP TC 7 conference on system modeling and optimization . 2016

机译：具有免疫反应的白血病竞争的复杂数学模型-最优控制方法。
5. Evaluating the role of dendritic cells in host immune response during human T cell leukemia virus type 1 (HTLV-1) infection using a transgenic mouse model system [D] . Rahman, Saifur 2010

机译：使用转基因小鼠模型系统评估树突状细胞在人T细胞白血病病毒1型（HTLV-1）感染期间宿主免疫反应中的作用
6. Genetic control of natural immunity to ecotropic mouse leukemia viruses: immune response genes. [O] . R C Nowinski 1976

机译：对嗜生性小鼠白血病病毒天然免疫力的遗传控制：免疫应答基因。
7. GENETIC CONTROL OF IMMUNE RESPONSES IN VITRO : II. CELLULAR REQUIREMENTS FOR THE DEVELOPMENT OF PRIMARY PLAQUE-FORMING CELL RESPONSES TO THE RANDOM TERPOLYMER L-GLUTAMIC ACID60-L-ALANINE30-L-TYROSINE10 (GAT) BY MOUSE SPLEEN CELLS IN VITRO [O] . Kapp, Judith A., Pierce, Carl W., Benacerraf, Baruj 1973

机译：体外免疫反应的遗传控制：II。小鼠脾细胞对随机三聚体L-谷氨酸60-L-丙氨酸30-L-酪氨酸10（GAT）的原始噬斑形成细胞反应的细胞要求

Genetic control of natural immunity to ecotropic mouse leukemia viruses: immune response genes.

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