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首页> 外文期刊>Infection and immunity >Serological comparison of canine rotavirus with various simian and human rotaviruses by plaque reduction neutralization and hemagglutination inhibition tests.
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Serological comparison of canine rotavirus with various simian and human rotaviruses by plaque reduction neutralization and hemagglutination inhibition tests.

机译：通过噬斑减少中和和血凝抑制试验比较犬轮状病毒与各种猿猴和人轮状病毒的血清学比较。

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By the plaque reduction neutralization test, the CU-1 strain of canine rotavirus was similar, if not identical, to three strains (no. 14, no. 15, and P) of the tentatively designated third human rotavirus serotype. In addition, strain CU-1 demonstrated a one-way antigenic relationship with two other strains (M and B) of the third human rotavirus serotype. The CU-1 strain of canine rotavirus hemagglutinated human group O, rhesus monkey, dog, sheep, and guinea pig erythrocytes. A two-way antigenic relationship between canine (CU-1) and simian (MMU 18006 and SA11) rotaviruses demonstrated previously by the plaque reduction neutralization test was confirmed further with two additional isolates (A79-10 and LSU 79C-36) of canine rotavirus by the plaque reduction neutralization test and the hemagglutination inhibition test. The CU-1 strain of canine rotavirus, which is known to be distinct from two well-characterized human rotavirus serotypes (Wa and DS-1), was also found to be distinct from the St. Thomas no. 4 strain, which is a newly defined fourth human rotavirus serotype. Thus, this canine strain, which is related antigenically to one of four human rotavirus serotypes, is another example of an animal rotavirus which shares serotype specificity with a human rotavirus.
机译：通过噬菌斑减少中和测试，犬轮状病毒的CU-1菌株与暂定为第三种人轮状病毒血清型的三种菌株（第14，第15和P型）相似（如果不相同）。此外，菌株CU-1与第三种人类轮状病毒血清型的另外两个菌株（M和B）表现出单向抗原关系。犬轮状病毒CU-1株对人O组，恒河猴，狗，绵羊和豚鼠的红细胞进行了血凝。先前通过噬菌斑减少中和试验证明的犬（CU-1）和猿猴（MMU 18006和SA11）轮状病毒之间存在双向抗原关系，另外还发现了犬轮状病毒的另外两种分离株（A79-10和LSU 79C-36）通过噬斑减少中和试验和血凝抑制试验。还发现犬轮状病毒的CU-1株与两种特征明确的人轮状病毒血清型（Wa和DS-1）不同，也不同于圣托马斯号。 4株，这是新定义的第四种人轮状病毒血清型。因此，与四种人轮状病毒血清型之一抗原性相关的犬品系是与人轮状病毒共享血清型特异性的动物轮状病毒的另一个实例。

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